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Distinct Actions of Akt1 on Skeletal Architecture and Function
Skeletal integrity is dependent on the coordinated actions of bone-forming osteoblasts and bone-resorbing osteoclasts, which recognize and respond to multiple environmental inputs. Here we have studied the roles in bone development and growth of Akt1 and Akt2, two closely related signaling proteins,...
Autores principales: | Mukherjee, Aditi, Larson, Emily A., Klein, Robert F., Rotwein, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963959/ https://www.ncbi.nlm.nih.gov/pubmed/24663486 http://dx.doi.org/10.1371/journal.pone.0093040 |
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