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An EGFR/HER2-Bispecific and Enediyne-Energized Fusion Protein Shows High Efficacy against Esophageal Cancer
Esophageal cancer is one of the most common cancers, and the 5-year survival rate is less than 10% due to lack of effective therapeutic agents. This study was to evaluate antitumor activity of Ec-LDP-Hr-AE, a recently developed bispecific enediyne-energized fusion protein targeting both epidermal gr...
Autores principales: | Guo, Xiao-Fang, Zhu, Xiao-Fei, Yang, Wan-Cai, Zhang, Sheng-Hua, Zhen, Yong-Su |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963964/ https://www.ncbi.nlm.nih.gov/pubmed/24664246 http://dx.doi.org/10.1371/journal.pone.0092986 |
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