Rad4 Mainly Functions in Chk1-Mediated DNA Damage Checkpoint Pathway as a Scaffold Protein in the Fission Yeast Schizosaccharomyces pombe

Rad4/Cut5 is a scaffold protein in the Chk1-mediated DNA damage checkpoint in S. pombe. However, whether it contains a robust ATR-activation domain (AAD) required for checkpoint signaling like its orthologs TopBP1 in humans and Dpb11 in budding yeast has been incompletely clear. To identify the puta...

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Detalles Bibliográficos
Autores principales: Yue, Ming, Zeng, Li, Singh, Amanpreet, Xu, Yongjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963969/
https://www.ncbi.nlm.nih.gov/pubmed/24663817
http://dx.doi.org/10.1371/journal.pone.0092936

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963969/
https://www.ncbi.nlm.nih.gov/pubmed/24663817
http://dx.doi.org/10.1371/journal.pone.0092936

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