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First Mnks degrading agents block phosphorylation of eIF4E, induce apoptosis, inhibit cell growth, migration and invasion in triple negative and Her2-overexpressing breast cancer cell lines

Some retinoic acid metabolism blocking agents (RAMBAs) are known to exhibit a wide range of anticancer activities by mechanisms that are still not completely resolved. This study investigated the anticancer efficacy and mechanism(s) of novel RAMBA retinamides (RRs) in triple negative and Her-2 overe...

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Detalles Bibliográficos
Autores principales:	Ramalingam, Senthilmurugan, Gediya, Lalji, Kwegyir-Afful, Andrew K., Ramamurthy, Vidya P., Purushottamachar, Puranik, Mbatia, Hannah, Njar, Vincent C. O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2014
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964227/ https://www.ncbi.nlm.nih.gov/pubmed/24504069

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