Cargando…

Hepatoprotective Herbs, Avicenna Viewpoint

BACKGROUND: Liver injury or dysfunction is considered as a serious health problem. The available synthetic drugs to treat liver disorders are expensive and cause further damage. Hence, hepatoprotective effects of some herbal drugs have been investigated, and one of the methods to choose herbs in ord...

Descripción completa

Detalles Bibliográficos
Autores principales: Shamsi-Baghbanan, Hamid, Sharifian, Afsaneh, Esmaeili, Somayeh, Minaei, Bagher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kowsar 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964420/
https://www.ncbi.nlm.nih.gov/pubmed/24719702
http://dx.doi.org/10.5812/ircmj.12313
_version_ 1782308640250658816
author Shamsi-Baghbanan, Hamid
Sharifian, Afsaneh
Esmaeili, Somayeh
Minaei, Bagher
author_facet Shamsi-Baghbanan, Hamid
Sharifian, Afsaneh
Esmaeili, Somayeh
Minaei, Bagher
author_sort Shamsi-Baghbanan, Hamid
collection PubMed
description BACKGROUND: Liver injury or dysfunction is considered as a serious health problem. The available synthetic drugs to treat liver disorders are expensive and cause further damage. Hence, hepatoprotective effects of some herbal drugs have been investigated, and one of the methods to choose herbs in order to study their biological effects is to search in ancient medical texts. Avicenna who is known as the prince of physicians had collected and classified Greek, Persian and Islamic medicine in the best possible way in the book of Canon in Arabic. OBJECTIVES: Avicenna’s book of The Canon of Medicine was reviewed to find the hepatoprotective herbs. PATIENTS AND METHODS: Three different versions of the Canon were prepared and utilized. To find scientific names of plants we took advantage of three botany references. All of the herbs were investigated on the basis of scientific data from hepatoprotective effects point of view. The searched term was “hepatoprotective” without narrowing and limiting. The searched databases included Cochrane library, Web of science, SID, Irandoc and IranMedex. RESULTS: 18 plants were found. 85% of the presented species, genus or families of plants were reported to have hepatoprotective properties and in the remaining 15% there were no reports of hepatoprotective effect. Flowers and fruits were the most used part of the plants. Most of the plants had simultaneous protective effects on multiple organs but the protective effect on the liver was mostly accompanied by protective effect on the stomach (83%). The average temperament of these herbs is "hot" in the 2nd phase of the 2nd grade, and "dry" in the 3rd phase of the 2nd grade. Hepatoprotective herbs mostly prescribed as a part of hepatoprotective compound drugs formula or other formula for liver diseases are Crocus sativus, Pistacia lentiscus, and Cinnamomum spp. CONCLUSIONS: Maybe there is common mechanism for protecting both liver and stomach. Aquilaria agallocha, Aquilaria malaccensis, and Ruscus aculeatus whose hepatoprotective effects have not yet been reported are considered as good candidates for future investigations. Given that Crocus sativus, and Cinnamomum spp are used as flavors in most countries, they will be introduced for more investigation in order to produce hepatoprotective drugs.
format Online
Article
Text
id pubmed-3964420
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Kowsar
record_format MEDLINE/PubMed
spelling pubmed-39644202014-04-09 Hepatoprotective Herbs, Avicenna Viewpoint Shamsi-Baghbanan, Hamid Sharifian, Afsaneh Esmaeili, Somayeh Minaei, Bagher Iran Red Crescent Med J Research Article BACKGROUND: Liver injury or dysfunction is considered as a serious health problem. The available synthetic drugs to treat liver disorders are expensive and cause further damage. Hence, hepatoprotective effects of some herbal drugs have been investigated, and one of the methods to choose herbs in order to study their biological effects is to search in ancient medical texts. Avicenna who is known as the prince of physicians had collected and classified Greek, Persian and Islamic medicine in the best possible way in the book of Canon in Arabic. OBJECTIVES: Avicenna’s book of The Canon of Medicine was reviewed to find the hepatoprotective herbs. PATIENTS AND METHODS: Three different versions of the Canon were prepared and utilized. To find scientific names of plants we took advantage of three botany references. All of the herbs were investigated on the basis of scientific data from hepatoprotective effects point of view. The searched term was “hepatoprotective” without narrowing and limiting. The searched databases included Cochrane library, Web of science, SID, Irandoc and IranMedex. RESULTS: 18 plants were found. 85% of the presented species, genus or families of plants were reported to have hepatoprotective properties and in the remaining 15% there were no reports of hepatoprotective effect. Flowers and fruits were the most used part of the plants. Most of the plants had simultaneous protective effects on multiple organs but the protective effect on the liver was mostly accompanied by protective effect on the stomach (83%). The average temperament of these herbs is "hot" in the 2nd phase of the 2nd grade, and "dry" in the 3rd phase of the 2nd grade. Hepatoprotective herbs mostly prescribed as a part of hepatoprotective compound drugs formula or other formula for liver diseases are Crocus sativus, Pistacia lentiscus, and Cinnamomum spp. CONCLUSIONS: Maybe there is common mechanism for protecting both liver and stomach. Aquilaria agallocha, Aquilaria malaccensis, and Ruscus aculeatus whose hepatoprotective effects have not yet been reported are considered as good candidates for future investigations. Given that Crocus sativus, and Cinnamomum spp are used as flavors in most countries, they will be introduced for more investigation in order to produce hepatoprotective drugs. Kowsar 2014-01-05 2014-01 /pmc/articles/PMC3964420/ /pubmed/24719702 http://dx.doi.org/10.5812/ircmj.12313 Text en Copyright © 2014, Iranian Red Crescent Medical Journal; Published by Kowsar Corp. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Shamsi-Baghbanan, Hamid
Sharifian, Afsaneh
Esmaeili, Somayeh
Minaei, Bagher
Hepatoprotective Herbs, Avicenna Viewpoint
title Hepatoprotective Herbs, Avicenna Viewpoint
title_full Hepatoprotective Herbs, Avicenna Viewpoint
title_fullStr Hepatoprotective Herbs, Avicenna Viewpoint
title_full_unstemmed Hepatoprotective Herbs, Avicenna Viewpoint
title_short Hepatoprotective Herbs, Avicenna Viewpoint
title_sort hepatoprotective herbs, avicenna viewpoint
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964420/
https://www.ncbi.nlm.nih.gov/pubmed/24719702
http://dx.doi.org/10.5812/ircmj.12313
work_keys_str_mv AT shamsibaghbananhamid hepatoprotectiveherbsavicennaviewpoint
AT sharifianafsaneh hepatoprotectiveherbsavicennaviewpoint
AT esmaeilisomayeh hepatoprotectiveherbsavicennaviewpoint
AT minaeibagher hepatoprotectiveherbsavicennaviewpoint