Cargando…

Yanshu spraying agent, a traditional Chinese medicine, relieves chronic pharyngitis in animals by anti-inflammatory and antibacterial effects

Chronic pharyngitis is chronic inflammation that is often caused by repeated occurrences of acute pharyngitis or upper respiratory tract infections, including Streptococcus and Staphylococcus. The present study aimed to investigate the effects of Yanshu spraying agent (Yanshu) in relieving chronic p...

Descripción completa

Detalles Bibliográficos
Autores principales: LU, CHENGWEN, SONG, YANQIN, ZHANG, JIANQIAO, DU, YUAN, WANG, TIAN, XUE, YUNLI, FU, FENGHUA, ZHANG, LEIMING
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964930/
https://www.ncbi.nlm.nih.gov/pubmed/24669264
http://dx.doi.org/10.3892/etm.2014.1524
_version_ 1782479260504555520
author LU, CHENGWEN
SONG, YANQIN
ZHANG, JIANQIAO
DU, YUAN
WANG, TIAN
XUE, YUNLI
FU, FENGHUA
ZHANG, LEIMING
author_facet LU, CHENGWEN
SONG, YANQIN
ZHANG, JIANQIAO
DU, YUAN
WANG, TIAN
XUE, YUNLI
FU, FENGHUA
ZHANG, LEIMING
author_sort LU, CHENGWEN
collection PubMed
description Chronic pharyngitis is chronic inflammation that is often caused by repeated occurrences of acute pharyngitis or upper respiratory tract infections, including Streptococcus and Staphylococcus. The present study aimed to investigate the effects of Yanshu spraying agent (Yanshu) in relieving chronic pharyngitis, as well as the possible underlying mechanisms. The results revealed that Yanshu inhibited chronic inflammation in ammonia-induced chronic pharyngitis in rabbits and cotton pellet-induced granuloma tissue formation in rats. Yanshu also demonstrated antibacterial effects on Streptococcus and Staphylococcus in vitro. Yanshu did not exhibit any effects on the immune system, including the spleen and thymus indexes, immunocyte count and monocyte-macrophage function, when compared with the effects of dexamethasone. Therefore, the results of the present study indicate that Yanshu may relieve chronic pharyngitis via its anti-inflammatory and antibacterial activities.
format Online
Article
Text
id pubmed-3964930
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher D.A. Spandidos
record_format MEDLINE/PubMed
spelling pubmed-39649302014-03-25 Yanshu spraying agent, a traditional Chinese medicine, relieves chronic pharyngitis in animals by anti-inflammatory and antibacterial effects LU, CHENGWEN SONG, YANQIN ZHANG, JIANQIAO DU, YUAN WANG, TIAN XUE, YUNLI FU, FENGHUA ZHANG, LEIMING Exp Ther Med Articles Chronic pharyngitis is chronic inflammation that is often caused by repeated occurrences of acute pharyngitis or upper respiratory tract infections, including Streptococcus and Staphylococcus. The present study aimed to investigate the effects of Yanshu spraying agent (Yanshu) in relieving chronic pharyngitis, as well as the possible underlying mechanisms. The results revealed that Yanshu inhibited chronic inflammation in ammonia-induced chronic pharyngitis in rabbits and cotton pellet-induced granuloma tissue formation in rats. Yanshu also demonstrated antibacterial effects on Streptococcus and Staphylococcus in vitro. Yanshu did not exhibit any effects on the immune system, including the spleen and thymus indexes, immunocyte count and monocyte-macrophage function, when compared with the effects of dexamethasone. Therefore, the results of the present study indicate that Yanshu may relieve chronic pharyngitis via its anti-inflammatory and antibacterial activities. D.A. Spandidos 2014-04 2014-02-06 /pmc/articles/PMC3964930/ /pubmed/24669264 http://dx.doi.org/10.3892/etm.2014.1524 Text en Copyright © 2014, Spandidos Publications http://creativecommons.org/licenses/by/3.0 This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Articles
LU, CHENGWEN
SONG, YANQIN
ZHANG, JIANQIAO
DU, YUAN
WANG, TIAN
XUE, YUNLI
FU, FENGHUA
ZHANG, LEIMING
Yanshu spraying agent, a traditional Chinese medicine, relieves chronic pharyngitis in animals by anti-inflammatory and antibacterial effects
title Yanshu spraying agent, a traditional Chinese medicine, relieves chronic pharyngitis in animals by anti-inflammatory and antibacterial effects
title_full Yanshu spraying agent, a traditional Chinese medicine, relieves chronic pharyngitis in animals by anti-inflammatory and antibacterial effects
title_fullStr Yanshu spraying agent, a traditional Chinese medicine, relieves chronic pharyngitis in animals by anti-inflammatory and antibacterial effects
title_full_unstemmed Yanshu spraying agent, a traditional Chinese medicine, relieves chronic pharyngitis in animals by anti-inflammatory and antibacterial effects
title_short Yanshu spraying agent, a traditional Chinese medicine, relieves chronic pharyngitis in animals by anti-inflammatory and antibacterial effects
title_sort yanshu spraying agent, a traditional chinese medicine, relieves chronic pharyngitis in animals by anti-inflammatory and antibacterial effects
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964930/
https://www.ncbi.nlm.nih.gov/pubmed/24669264
http://dx.doi.org/10.3892/etm.2014.1524
work_keys_str_mv AT luchengwen yanshusprayingagentatraditionalchinesemedicinerelieveschronicpharyngitisinanimalsbyantiinflammatoryandantibacterialeffects
AT songyanqin yanshusprayingagentatraditionalchinesemedicinerelieveschronicpharyngitisinanimalsbyantiinflammatoryandantibacterialeffects
AT zhangjianqiao yanshusprayingagentatraditionalchinesemedicinerelieveschronicpharyngitisinanimalsbyantiinflammatoryandantibacterialeffects
AT duyuan yanshusprayingagentatraditionalchinesemedicinerelieveschronicpharyngitisinanimalsbyantiinflammatoryandantibacterialeffects
AT wangtian yanshusprayingagentatraditionalchinesemedicinerelieveschronicpharyngitisinanimalsbyantiinflammatoryandantibacterialeffects
AT xueyunli yanshusprayingagentatraditionalchinesemedicinerelieveschronicpharyngitisinanimalsbyantiinflammatoryandantibacterialeffects
AT fufenghua yanshusprayingagentatraditionalchinesemedicinerelieveschronicpharyngitisinanimalsbyantiinflammatoryandantibacterialeffects
AT zhangleiming yanshusprayingagentatraditionalchinesemedicinerelieveschronicpharyngitisinanimalsbyantiinflammatoryandantibacterialeffects