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Yanshu spraying agent, a traditional Chinese medicine, relieves chronic pharyngitis in animals by anti-inflammatory and antibacterial effects
Chronic pharyngitis is chronic inflammation that is often caused by repeated occurrences of acute pharyngitis or upper respiratory tract infections, including Streptococcus and Staphylococcus. The present study aimed to investigate the effects of Yanshu spraying agent (Yanshu) in relieving chronic p...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964930/ https://www.ncbi.nlm.nih.gov/pubmed/24669264 http://dx.doi.org/10.3892/etm.2014.1524 |
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author | LU, CHENGWEN SONG, YANQIN ZHANG, JIANQIAO DU, YUAN WANG, TIAN XUE, YUNLI FU, FENGHUA ZHANG, LEIMING |
author_facet | LU, CHENGWEN SONG, YANQIN ZHANG, JIANQIAO DU, YUAN WANG, TIAN XUE, YUNLI FU, FENGHUA ZHANG, LEIMING |
author_sort | LU, CHENGWEN |
collection | PubMed |
description | Chronic pharyngitis is chronic inflammation that is often caused by repeated occurrences of acute pharyngitis or upper respiratory tract infections, including Streptococcus and Staphylococcus. The present study aimed to investigate the effects of Yanshu spraying agent (Yanshu) in relieving chronic pharyngitis, as well as the possible underlying mechanisms. The results revealed that Yanshu inhibited chronic inflammation in ammonia-induced chronic pharyngitis in rabbits and cotton pellet-induced granuloma tissue formation in rats. Yanshu also demonstrated antibacterial effects on Streptococcus and Staphylococcus in vitro. Yanshu did not exhibit any effects on the immune system, including the spleen and thymus indexes, immunocyte count and monocyte-macrophage function, when compared with the effects of dexamethasone. Therefore, the results of the present study indicate that Yanshu may relieve chronic pharyngitis via its anti-inflammatory and antibacterial activities. |
format | Online Article Text |
id | pubmed-3964930 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | D.A. Spandidos |
record_format | MEDLINE/PubMed |
spelling | pubmed-39649302014-03-25 Yanshu spraying agent, a traditional Chinese medicine, relieves chronic pharyngitis in animals by anti-inflammatory and antibacterial effects LU, CHENGWEN SONG, YANQIN ZHANG, JIANQIAO DU, YUAN WANG, TIAN XUE, YUNLI FU, FENGHUA ZHANG, LEIMING Exp Ther Med Articles Chronic pharyngitis is chronic inflammation that is often caused by repeated occurrences of acute pharyngitis or upper respiratory tract infections, including Streptococcus and Staphylococcus. The present study aimed to investigate the effects of Yanshu spraying agent (Yanshu) in relieving chronic pharyngitis, as well as the possible underlying mechanisms. The results revealed that Yanshu inhibited chronic inflammation in ammonia-induced chronic pharyngitis in rabbits and cotton pellet-induced granuloma tissue formation in rats. Yanshu also demonstrated antibacterial effects on Streptococcus and Staphylococcus in vitro. Yanshu did not exhibit any effects on the immune system, including the spleen and thymus indexes, immunocyte count and monocyte-macrophage function, when compared with the effects of dexamethasone. Therefore, the results of the present study indicate that Yanshu may relieve chronic pharyngitis via its anti-inflammatory and antibacterial activities. D.A. Spandidos 2014-04 2014-02-06 /pmc/articles/PMC3964930/ /pubmed/24669264 http://dx.doi.org/10.3892/etm.2014.1524 Text en Copyright © 2014, Spandidos Publications http://creativecommons.org/licenses/by/3.0 This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited. |
spellingShingle | Articles LU, CHENGWEN SONG, YANQIN ZHANG, JIANQIAO DU, YUAN WANG, TIAN XUE, YUNLI FU, FENGHUA ZHANG, LEIMING Yanshu spraying agent, a traditional Chinese medicine, relieves chronic pharyngitis in animals by anti-inflammatory and antibacterial effects |
title | Yanshu spraying agent, a traditional Chinese medicine, relieves chronic pharyngitis in animals by anti-inflammatory and antibacterial effects |
title_full | Yanshu spraying agent, a traditional Chinese medicine, relieves chronic pharyngitis in animals by anti-inflammatory and antibacterial effects |
title_fullStr | Yanshu spraying agent, a traditional Chinese medicine, relieves chronic pharyngitis in animals by anti-inflammatory and antibacterial effects |
title_full_unstemmed | Yanshu spraying agent, a traditional Chinese medicine, relieves chronic pharyngitis in animals by anti-inflammatory and antibacterial effects |
title_short | Yanshu spraying agent, a traditional Chinese medicine, relieves chronic pharyngitis in animals by anti-inflammatory and antibacterial effects |
title_sort | yanshu spraying agent, a traditional chinese medicine, relieves chronic pharyngitis in animals by anti-inflammatory and antibacterial effects |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964930/ https://www.ncbi.nlm.nih.gov/pubmed/24669264 http://dx.doi.org/10.3892/etm.2014.1524 |
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