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NPInter v2.0: an updated database of ncRNA interactions

NPInter (http://www.bioinfo.org/NPInter) is a database that integrates experimentally verified functional interactions between noncoding RNAs (excluding tRNAs and rRNAs) and other biomolecules (proteins, RNAs and genomic DNAs). Extensive studies on ncRNA interactions have shown that ncRNAs could act...

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Detalles Bibliográficos
Autores principales: Yuan, Jiao, Wu, Wei, Xie, Chaoyong, Zhao, Guoguang, Zhao, Yi, Chen, Runsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965026/
https://www.ncbi.nlm.nih.gov/pubmed/24217916
http://dx.doi.org/10.1093/nar/gkt1057
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author Yuan, Jiao
Wu, Wei
Xie, Chaoyong
Zhao, Guoguang
Zhao, Yi
Chen, Runsheng
author_facet Yuan, Jiao
Wu, Wei
Xie, Chaoyong
Zhao, Guoguang
Zhao, Yi
Chen, Runsheng
author_sort Yuan, Jiao
collection PubMed
description NPInter (http://www.bioinfo.org/NPInter) is a database that integrates experimentally verified functional interactions between noncoding RNAs (excluding tRNAs and rRNAs) and other biomolecules (proteins, RNAs and genomic DNAs). Extensive studies on ncRNA interactions have shown that ncRNAs could act as part of enzymatic or structural complexes, gene regulators or other functional elements. With the development of high-throughput biotechnology, such as cross-linking immunoprecipitation and high-throughput sequencing (CLIP-seq), the number of known ncRNA interactions, especially those formed by protein binding, has grown rapidly in recent years. In this work, we updated NPInter to version 2.0 by collecting ncRNA interactions from recent literature and related databases, expanding the number of entries to 201 107 covering 18 species. In addition, NPInter v2.0 incorporated a service for the BLAST alignment search as well as visualization of interactions.
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spelling pubmed-39650262014-03-25 NPInter v2.0: an updated database of ncRNA interactions Yuan, Jiao Wu, Wei Xie, Chaoyong Zhao, Guoguang Zhao, Yi Chen, Runsheng Nucleic Acids Res I. Nucleic acid sequence, structure and regulation NPInter (http://www.bioinfo.org/NPInter) is a database that integrates experimentally verified functional interactions between noncoding RNAs (excluding tRNAs and rRNAs) and other biomolecules (proteins, RNAs and genomic DNAs). Extensive studies on ncRNA interactions have shown that ncRNAs could act as part of enzymatic or structural complexes, gene regulators or other functional elements. With the development of high-throughput biotechnology, such as cross-linking immunoprecipitation and high-throughput sequencing (CLIP-seq), the number of known ncRNA interactions, especially those formed by protein binding, has grown rapidly in recent years. In this work, we updated NPInter to version 2.0 by collecting ncRNA interactions from recent literature and related databases, expanding the number of entries to 201 107 covering 18 species. In addition, NPInter v2.0 incorporated a service for the BLAST alignment search as well as visualization of interactions. Oxford University Press 2014-01-01 2013-11-11 /pmc/articles/PMC3965026/ /pubmed/24217916 http://dx.doi.org/10.1093/nar/gkt1057 Text en © Crown copyright 2013.
spellingShingle I. Nucleic acid sequence, structure and regulation
Yuan, Jiao
Wu, Wei
Xie, Chaoyong
Zhao, Guoguang
Zhao, Yi
Chen, Runsheng
NPInter v2.0: an updated database of ncRNA interactions
title NPInter v2.0: an updated database of ncRNA interactions
title_full NPInter v2.0: an updated database of ncRNA interactions
title_fullStr NPInter v2.0: an updated database of ncRNA interactions
title_full_unstemmed NPInter v2.0: an updated database of ncRNA interactions
title_short NPInter v2.0: an updated database of ncRNA interactions
title_sort npinter v2.0: an updated database of ncrna interactions
topic I. Nucleic acid sequence, structure and regulation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965026/
https://www.ncbi.nlm.nih.gov/pubmed/24217916
http://dx.doi.org/10.1093/nar/gkt1057
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