HoPaCI-DB: host-Pseudomonas and Coxiella interaction database

Bacterial infectious diseases are the result of multifactorial processes affected by the interplay between virulence factors and host targets. The host-Pseudomonas and Coxiella interaction database (HoPaCI-DB) is a publicly available manually curated integrative database (http://mips.helmholtz-muenc...

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Detalles Bibliográficos
Autores principales: Bleves, Sophie, Dunger, Irmtraud, Walter, Mathias C., Frangoulidis, Dimitrios, Kastenmüller, Gabi, Voulhoux, Romé, Ruepp, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
IV. Viruses, bacteria, protozoa and fungi
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965080/
https://www.ncbi.nlm.nih.gov/pubmed/24137008
http://dx.doi.org/10.1093/nar/gkt925
Descripción
Sumario:Bacterial infectious diseases are the result of multifactorial processes affected by the interplay between virulence factors and host targets. The host-Pseudomonas and Coxiella interaction database (HoPaCI-DB) is a publicly available manually curated integrative database (http://mips.helmholtz-muenchen.de/HoPaCI/) of host–pathogen interaction data from Pseudomonas aeruginosa and Coxiella burnetii. The resource provides structured information on 3585 experimentally validated interactions between molecules, bioprocesses and cellular structures extracted from the scientific literature. Systematic annotation and interactive graphical representation of disease networks make HoPaCI-DB a versatile knowledge base for biologists and network biology approaches.

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