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The Kinesin-12 Kif15 is a processive track-switching tetramer
Kinesin-12 motors are a little studied branch of the kinesin superfamily with the human protein (Kif15) implicated in spindle mechanics and chromosome movement. In this study, we reconstitute full-length hKif15 and its microtubule-targeting factor hTpx2 in vitro to gain insight into the motors mode...
Autores principales: | Drechsler, Hauke, McHugh, Toni, Singleton, Martin R, Carter, Nicholas J, McAinsh, Andrew D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965211/ https://www.ncbi.nlm.nih.gov/pubmed/24668168 http://dx.doi.org/10.7554/eLife.01724 |
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