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Anesthesia-induced hypothermia mediates decreased ARC gene and protein expression through ERK/MAPK inactivation
Several anesthetics have been reported to suppress the transcription of a number of genes, including Arc, also known as Arg3.1, an immediate early gene that plays a significant role in memory consolidation. The purpose of this study was to explore the mechanism of anesthesia-mediated depression in A...
Autores principales: | Whittington, Robert A., Bretteville, Alexis, Virág, László, Emala, Charles W., Maurin, Thomas O., Marcouiller, François, Julien, Carl, Petry, Franck R., El-Khoury, Noura B., Morin, Françoise, Charron, Jean, Planel, Emmanuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965357/ https://www.ncbi.nlm.nih.gov/pubmed/24045785 http://dx.doi.org/10.1038/srep01388 |
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