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Effect of Intraoperative High-Dose Remifentanil on Postoperative Pain: A Prospective, Double Blind, Randomized Clinical Trial

BACKGROUND: Remifentanil, an ultra-short-acting opioid, is widely used for pain control during surgery. However, regular dose (RD) remifentanil exacerbates postoperative pain in a dose-dependent manner. Recent studies suggest that high-dose (HD) remifentanil offers sustained analgesia in experimenta...

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Detalles Bibliográficos
Autores principales: Zhang, Yan-Ling, Ou, Peng, Lu, Xiang-Hang, Chen, Yan-Ping, Xu, Jun-Mei, Dai, Ru-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965388/
https://www.ncbi.nlm.nih.gov/pubmed/24667391
http://dx.doi.org/10.1371/journal.pone.0091454