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Assessing the Impact of Copy Number Variants on miRNA Genes in Autism by Monte Carlo Simulation

Autism Spectrum Disorders (ASDs) are childhood neurodevelopmental disorders with complex genetic origins. Previous studies have investigated the role of de novo Copy Number Variants (CNVs) and microRNAs as important but distinct etiological factors in ASD. We developed a novel computational procedur...

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Detalles Bibliográficos
Autores principales: Marrale, Maurizio, Albanese, Nadia Ninfa, Calì, Francesco, Romano, Valentino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965395/
https://www.ncbi.nlm.nih.gov/pubmed/24667286
http://dx.doi.org/10.1371/journal.pone.0090947