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Assessing the Impact of Copy Number Variants on miRNA Genes in Autism by Monte Carlo Simulation
Autism Spectrum Disorders (ASDs) are childhood neurodevelopmental disorders with complex genetic origins. Previous studies have investigated the role of de novo Copy Number Variants (CNVs) and microRNAs as important but distinct etiological factors in ASD. We developed a novel computational procedur...
Autores principales: | Marrale, Maurizio, Albanese, Nadia Ninfa, Calì, Francesco, Romano, Valentino |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965395/ https://www.ncbi.nlm.nih.gov/pubmed/24667286 http://dx.doi.org/10.1371/journal.pone.0090947 |
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