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Open Source Software to Control Bioflo Bioreactors

Bioreactors are designed to support highly controlled environments for growth of tissues, cell cultures or microbial cultures. A variety of bioreactors are commercially available, often including sophisticated software to enhance the functionality of the bioreactor. However, experiments that the bio...

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Detalles Bibliográficos
Autores principales: Burdge, David A., Libourel, Igor G. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965399/
https://www.ncbi.nlm.nih.gov/pubmed/24667828
http://dx.doi.org/10.1371/journal.pone.0092108
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author Burdge, David A.
Libourel, Igor G. L.
author_facet Burdge, David A.
Libourel, Igor G. L.
author_sort Burdge, David A.
collection PubMed
description Bioreactors are designed to support highly controlled environments for growth of tissues, cell cultures or microbial cultures. A variety of bioreactors are commercially available, often including sophisticated software to enhance the functionality of the bioreactor. However, experiments that the bioreactor hardware can support, but that were not envisioned during the software design cannot be performed without developing custom software. In addition, support for third party or custom designed auxiliary hardware is often sparse or absent. This work presents flexible open source freeware for the control of bioreactors of the Bioflo product family. The functionality of the software includes setpoint control, data logging, and protocol execution. Auxiliary hardware can be easily integrated and controlled through an integrated plugin interface without altering existing software. Simple experimental protocols can be entered as a CSV scripting file, and a Python-based protocol execution model is included for more demanding conditional experimental control. The software was designed to be a more flexible and free open source alternative to the commercially available solution. The source code and various auxiliary hardware plugins are publicly available for download from https://github.com/LibourelLab/BiofloSoftware. In addition to the source code, the software was compiled and packaged as a self-installing file for 32 and 64 bit windows operating systems. The compiled software will be able to control a Bioflo system, and will not require the installation of LabVIEW.
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spelling pubmed-39653992014-03-27 Open Source Software to Control Bioflo Bioreactors Burdge, David A. Libourel, Igor G. L. PLoS One Research Article Bioreactors are designed to support highly controlled environments for growth of tissues, cell cultures or microbial cultures. A variety of bioreactors are commercially available, often including sophisticated software to enhance the functionality of the bioreactor. However, experiments that the bioreactor hardware can support, but that were not envisioned during the software design cannot be performed without developing custom software. In addition, support for third party or custom designed auxiliary hardware is often sparse or absent. This work presents flexible open source freeware for the control of bioreactors of the Bioflo product family. The functionality of the software includes setpoint control, data logging, and protocol execution. Auxiliary hardware can be easily integrated and controlled through an integrated plugin interface without altering existing software. Simple experimental protocols can be entered as a CSV scripting file, and a Python-based protocol execution model is included for more demanding conditional experimental control. The software was designed to be a more flexible and free open source alternative to the commercially available solution. The source code and various auxiliary hardware plugins are publicly available for download from https://github.com/LibourelLab/BiofloSoftware. In addition to the source code, the software was compiled and packaged as a self-installing file for 32 and 64 bit windows operating systems. The compiled software will be able to control a Bioflo system, and will not require the installation of LabVIEW. Public Library of Science 2014-03-25 /pmc/articles/PMC3965399/ /pubmed/24667828 http://dx.doi.org/10.1371/journal.pone.0092108 Text en © 2014 Libourel, Burdge http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Burdge, David A.
Libourel, Igor G. L.
Open Source Software to Control Bioflo Bioreactors
title Open Source Software to Control Bioflo Bioreactors
title_full Open Source Software to Control Bioflo Bioreactors
title_fullStr Open Source Software to Control Bioflo Bioreactors
title_full_unstemmed Open Source Software to Control Bioflo Bioreactors
title_short Open Source Software to Control Bioflo Bioreactors
title_sort open source software to control bioflo bioreactors
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965399/
https://www.ncbi.nlm.nih.gov/pubmed/24667828
http://dx.doi.org/10.1371/journal.pone.0092108
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