Calcineurin/NFAT Signaling Represses Genes Vamp1 and Vamp2 via PMCA-Dependent Mechanism during Dopamine Secretion by Pheochromocytoma Cells

BACKGROUND: Plasma membrane Ca(2+)-ATPases (PMCA) extrude Ca(2+) ions out of the cell and contribute to generation of calcium oscillations. Calcium signaling is crucial for transcriptional regulation of dopamine secretion by neuroendocrine PC12 cells. Low resting [Ca(2+)](c) in PC12 cells is maintai...

Descripción completa

Detalles Bibliográficos
Autores principales: Kosiorek, Michalina, Zylinska, Ludmila, Zablocki, Krzysztof, Pikula, Slawomir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965406/
https://www.ncbi.nlm.nih.gov/pubmed/24667359
http://dx.doi.org/10.1371/journal.pone.0092176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965406/
https://www.ncbi.nlm.nih.gov/pubmed/24667359
http://dx.doi.org/10.1371/journal.pone.0092176

Ejemplares similares