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GABA and Glutamate Pathways Are Spatially and Developmentally Affected in the Brain of Mecp2-Deficient Mice

Proper brain functioning requires a fine-tuning between excitatory and inhibitory neurotransmission, a balance maintained through the regulation and release of glutamate and GABA. Rett syndrome (RTT) is a rare genetic disorder caused by mutations in the methyl-CpG binding protein 2 (MECP2) gene affe...

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Detalles Bibliográficos
Autores principales: El-Khoury, Rita, Panayotis, Nicolas, Matagne, Valérie, Ghata, Adeline, Villard, Laurent, Roux, Jean-Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965407/
https://www.ncbi.nlm.nih.gov/pubmed/24667344
http://dx.doi.org/10.1371/journal.pone.0092169