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Biphasic Role of Chondroitin Sulfate in Cardiac Differentiation of Embryonic Stem Cells through Inhibition of Wnt/β-Catenin Signaling

The glycosaminoglycan chondroitin sulfate is a critical component of proteoglycans on the cell surface and in the extracellular matrix. As such, chondroitin sulfate side chains and the sulfation balance of chondroitin play important roles in the control of signaling pathways, and have a functional i...

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Detalles Bibliográficos
Autores principales: Prinz, Robert D., Willis, Catherine M., van Kuppevelt, Toin H., Klüppel, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965413/
https://www.ncbi.nlm.nih.gov/pubmed/24667694
http://dx.doi.org/10.1371/journal.pone.0092381

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