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Mesenchymal Stem Cells from Rats with Chronic Kidney Disease Exhibit Premature Senescence and Loss of Regenerative Potential

Mesenchymal stem cell (MSC) transplantation has the potential for organ repair. Nevertheless, some factors might lessen the regenerative potential of MSCs, e.g. donor age or systemic disease. It is thus important to carefully assess the patient's suitability for autologous MSC transplantation....

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Detalles Bibliográficos
Autores principales: Klinkhammer, Barbara Mara, Kramann, Rafael, Mallau, Monika, Makowska, Anna, van Roeyen, Claudia Renate, Rong, Song, Buecher, Eva Bettina, Boor, Peter, Kovacova, Katarina, Zok, Stephanie, Denecke, Bernd, Stuettgen, Esther, Otten, Simon, Floege, Juergen, Kunter, Uta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965415/
https://www.ncbi.nlm.nih.gov/pubmed/24667162
http://dx.doi.org/10.1371/journal.pone.0092115