Low 2012–13 Influenza Vaccine Effectiveness Associated with Mutation in the Egg-Adapted H3N2 Vaccine Strain Not Antigenic Drift in Circulating Viruses

BACKGROUND: Influenza vaccine effectiveness (VE) is generally interpreted in the context of vaccine match/mismatch to circulating strains with evolutionary drift in the latter invoked to explain reduced protection. During the 2012–13 season, however, detailed genotypic and phenotypic characterizatio...

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Detalles Bibliográficos
Autores principales: Skowronski, Danuta M., Janjua, Naveed Z., De Serres, Gaston, Sabaiduc, Suzana, Eshaghi, Alireza, Dickinson, James A., Fonseca, Kevin, Winter, Anne-Luise, Gubbay, Jonathan B., Krajden, Mel, Petric, Martin, Charest, Hugues, Bastien, Nathalie, Kwindt, Trijntje L., Mahmud, Salaheddin M., Van Caeseele, Paul, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965421/
https://www.ncbi.nlm.nih.gov/pubmed/24667168
http://dx.doi.org/10.1371/journal.pone.0092153

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