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Design of Optimally Constructed Metabolic Networks of Minimal Functionality
BACKGROUND: Metabolic engineering aims to design microorganisms that will generate a product of interest at high yield. Thus, a variety of in silico modeling strategies has been applied successfully, including the concepts of elementary flux modes (EFMs) and constrained minimal cut sets (cMCSs). The...
Autores principales: | Ruckerbauer, David E., Jungreuthmayer, Christian, Zanghellini, Jürgen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965433/ https://www.ncbi.nlm.nih.gov/pubmed/24667792 http://dx.doi.org/10.1371/journal.pone.0092583 |
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