A Novel Functional TagSNP Rs7560488 in the DNMT3A1 Promoter Is Associated with Susceptibility to Gastric Cancer by Modulating Promoter Activity

DNA-methyltransferase (DNMT)-3A which contains DNMT3A1 and DNMT3A2 isoforms have been suggested to play a crucial role in carcinogenesis and showed aberrant expression in most cancers. Accumulated evidences also indicated that single nucleotide polymorphisms (SNP) in DNMT genes were associated with...

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Detalles Bibliográficos
Autores principales: Wu, Huazhang, Zhang, Kun, Gong, Pihai, Qiao, Fengchang, Wang, Ling, Cui, He, Sui, Xinyuan, Gao, Jifan, Fan, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965498/
https://www.ncbi.nlm.nih.gov/pubmed/24667323
http://dx.doi.org/10.1371/journal.pone.0092911

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965498/
https://www.ncbi.nlm.nih.gov/pubmed/24667323
http://dx.doi.org/10.1371/journal.pone.0092911

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