Light-Mediated Kinetic Control Reveals the Temporal Effect of the Raf/MEK/ERK Pathway in PC12 Cell Neurite Outgrowth

It has been proposed that differential activation kinetics allows cells to use a common set of signaling pathways to specify distinct cellular outcomes. For example, nerve growth factor (NGF) and epidermal growth factor (EGF) induce different activation kinetics of the Raf/MEK/ERK signaling pathway...

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Detalles Bibliográficos
Autores principales: Zhang, Kai, Duan, Liting, Ong, Qunxiang, Lin, Ziliang, Varman, Pooja Mahendra, Sung, Kijung, Cui, Bianxiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965503/
https://www.ncbi.nlm.nih.gov/pubmed/24667437
http://dx.doi.org/10.1371/journal.pone.0092917

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