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Impact of body mass index on the prognosis of Korean women with endometrioid adenocarcinoma of the uterus: A cohort study

OBJECTIVE: To analyze how pretreatment body mass index relates to known endometrial cancer prognostic factors and how it impacts the disease-free survival and cause-specific survival of Korean women with endometrial cancer. METHODS: The patients were divided into the non-obese (<25 kg/m(2)) and o...

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Autores principales: Park, Jeong-Yeol, Cho, Jae-Hyun, Min, Jin-Young, Kim, Dae-Yeon, Kim, Jong-Hyeok, Kim, Yong-Man, Kim, Young-Tak, Nam, Joo-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Obstetrics and Gynecology; Korean Society of Contraception and Reproductive Health; Korean Society of Gynecologic Endocrinology; Korean Society of Gynecologic Endoscopy and Minimal Invasive Surgery; Korean Society of Maternal Fetal Medicine; Korean Society of Ultrasound in Obstetrics and Gynecology; Korean Urogynecologic Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965694/
https://www.ncbi.nlm.nih.gov/pubmed/24678484
http://dx.doi.org/10.5468/ogs.2014.57.2.115
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author Park, Jeong-Yeol
Cho, Jae-Hyun
Min, Jin-Young
Kim, Dae-Yeon
Kim, Jong-Hyeok
Kim, Yong-Man
Kim, Young-Tak
Nam, Joo-Hyun
author_facet Park, Jeong-Yeol
Cho, Jae-Hyun
Min, Jin-Young
Kim, Dae-Yeon
Kim, Jong-Hyeok
Kim, Yong-Man
Kim, Young-Tak
Nam, Joo-Hyun
author_sort Park, Jeong-Yeol
collection PubMed
description OBJECTIVE: To analyze how pretreatment body mass index relates to known endometrial cancer prognostic factors and how it impacts the disease-free survival and cause-specific survival of Korean women with endometrial cancer. METHODS: The patients were divided into the non-obese (<25 kg/m(2)) and obese groups (≥25 kg/m(2)) according to their pretreatment body mass index. The 25 kg/m(2) body mass index cut-off was based on the World Health Organization criteria for Asian people. The two groups were compared in terms of their clinicopathological characteristics and survival outcomes. RESULTS: A total of 213 consecutive patients with endometrioid adenocarcinoma of the uterus met the eligibility criteria of this study and were included in the analysis. Of these patients, 105 patients had a body mass index less than 25 kg/m(2) (non-obese group) and 108 patients had a body mass index equal to or more than 25 kg/m(2) (obese group). The two groups did not differ in terms of age, menopause, parity, height, FIGO (International Federation of Obstetrics and Gynecology) stage, tumor grade, tumor size, myometrial invasion, lymphovascular space invasion, cytology, and lymph node metastasis. Body mass index was not a significant factor for disease-free and cause-specific survival in univariate analysis, and after adjusting for all prognostic factors that were significant in univariate analysis, it did not associate significantly with disease-free and cause-specific survival. CONCLUSION: In Korean women with endometrioid adenocarcinoma of the uterus, a high pretreatment body mass index did not associate with other prognostic factors and had little impact on the disease-free survival and cause-specific survival of these women.
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spelling pubmed-39656942014-03-27 Impact of body mass index on the prognosis of Korean women with endometrioid adenocarcinoma of the uterus: A cohort study Park, Jeong-Yeol Cho, Jae-Hyun Min, Jin-Young Kim, Dae-Yeon Kim, Jong-Hyeok Kim, Yong-Man Kim, Young-Tak Nam, Joo-Hyun Obstet Gynecol Sci Original Article OBJECTIVE: To analyze how pretreatment body mass index relates to known endometrial cancer prognostic factors and how it impacts the disease-free survival and cause-specific survival of Korean women with endometrial cancer. METHODS: The patients were divided into the non-obese (<25 kg/m(2)) and obese groups (≥25 kg/m(2)) according to their pretreatment body mass index. The 25 kg/m(2) body mass index cut-off was based on the World Health Organization criteria for Asian people. The two groups were compared in terms of their clinicopathological characteristics and survival outcomes. RESULTS: A total of 213 consecutive patients with endometrioid adenocarcinoma of the uterus met the eligibility criteria of this study and were included in the analysis. Of these patients, 105 patients had a body mass index less than 25 kg/m(2) (non-obese group) and 108 patients had a body mass index equal to or more than 25 kg/m(2) (obese group). The two groups did not differ in terms of age, menopause, parity, height, FIGO (International Federation of Obstetrics and Gynecology) stage, tumor grade, tumor size, myometrial invasion, lymphovascular space invasion, cytology, and lymph node metastasis. Body mass index was not a significant factor for disease-free and cause-specific survival in univariate analysis, and after adjusting for all prognostic factors that were significant in univariate analysis, it did not associate significantly with disease-free and cause-specific survival. CONCLUSION: In Korean women with endometrioid adenocarcinoma of the uterus, a high pretreatment body mass index did not associate with other prognostic factors and had little impact on the disease-free survival and cause-specific survival of these women. Korean Society of Obstetrics and Gynecology; Korean Society of Contraception and Reproductive Health; Korean Society of Gynecologic Endocrinology; Korean Society of Gynecologic Endoscopy and Minimal Invasive Surgery; Korean Society of Maternal Fetal Medicine; Korean Society of Ultrasound in Obstetrics and Gynecology; Korean Urogynecologic Society 2014-03 2014-03-15 /pmc/articles/PMC3965694/ /pubmed/24678484 http://dx.doi.org/10.5468/ogs.2014.57.2.115 Text en Copyright © 2014 Korean Society of Obstetrics and Gynecology http://creativecommons.org/licenses/by-nc/3.0/ Articles published in Obstet Gynecol Sci are open-access, distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Park, Jeong-Yeol
Cho, Jae-Hyun
Min, Jin-Young
Kim, Dae-Yeon
Kim, Jong-Hyeok
Kim, Yong-Man
Kim, Young-Tak
Nam, Joo-Hyun
Impact of body mass index on the prognosis of Korean women with endometrioid adenocarcinoma of the uterus: A cohort study
title Impact of body mass index on the prognosis of Korean women with endometrioid adenocarcinoma of the uterus: A cohort study
title_full Impact of body mass index on the prognosis of Korean women with endometrioid adenocarcinoma of the uterus: A cohort study
title_fullStr Impact of body mass index on the prognosis of Korean women with endometrioid adenocarcinoma of the uterus: A cohort study
title_full_unstemmed Impact of body mass index on the prognosis of Korean women with endometrioid adenocarcinoma of the uterus: A cohort study
title_short Impact of body mass index on the prognosis of Korean women with endometrioid adenocarcinoma of the uterus: A cohort study
title_sort impact of body mass index on the prognosis of korean women with endometrioid adenocarcinoma of the uterus: a cohort study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965694/
https://www.ncbi.nlm.nih.gov/pubmed/24678484
http://dx.doi.org/10.5468/ogs.2014.57.2.115
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