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Characteristics of thyroid nodules in infant with congenital hypothyroidism
PURPOSE: This study aimed to assess the characteristics of thyroid nodules among infants diagnosed with congenital hypothyroidism. METHODS: A retrospective study of 660 infants (374 males, 286 females) diagnosed with congenital hypothyroidism was carried out at the Pediatric Endocrine Clinic in Soon...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Pediatric Society
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965800/ https://www.ncbi.nlm.nih.gov/pubmed/24678333 http://dx.doi.org/10.3345/kjp.2014.57.2.85 |
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author | Youn, Seo Young Lee, Jeong Ho Chang, Yun-Woo Lee, Dong Hwan |
author_facet | Youn, Seo Young Lee, Jeong Ho Chang, Yun-Woo Lee, Dong Hwan |
author_sort | Youn, Seo Young |
collection | PubMed |
description | PURPOSE: This study aimed to assess the characteristics of thyroid nodules among infants diagnosed with congenital hypothyroidism. METHODS: A retrospective study of 660 infants (374 males, 286 females) diagnosed with congenital hypothyroidism was carried out at the Pediatric Endocrine Clinic in Soonchunhyang University Hospital, Korea, between May 2003 and February 2013. The average age at diagnosis was 1.16±1.68 months. RESULTS: Of the 28 patients (4.2%) with thyroid nodules, 17 (2.6%) had cystic thyroid nodules and 11 (1.6%) had solid thyroid nodules. There were no significant differences in gender or age between congenital hypothyroidism patients who hadthyroid nodules and those who did not. All nodules were asymptomatic. The average age at diagnosis of congenital hypothyroidism with nodules was 1.42±1.39 months. All detected nodules measured less than 1 cm in diameter. Twenty-two of the 28 infants (78.6%) had only one nodule, while multiple nodules were found in 6 infants (21.4%). Of the 28 infants diagnosed with nodules, 16 underwent thyroid ultrasonography during follow-up and 8 of them (50%) showed no signs of nodules at thyroid ultrasonography. CONCLUSION: The prevalence of thyroid nodules in infants with congenital hypothyroidism was 4.2%. Most thyroid nodules were small in size and benign, disappearing during follow-up observation. We therefore conclude that thyroid nodules in infants with congenital hypothyroidism can simply be observed and do not require direct treatment. |
format | Online Article Text |
id | pubmed-3965800 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | The Korean Pediatric Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-39658002014-03-27 Characteristics of thyroid nodules in infant with congenital hypothyroidism Youn, Seo Young Lee, Jeong Ho Chang, Yun-Woo Lee, Dong Hwan Korean J Pediatr Original Article PURPOSE: This study aimed to assess the characteristics of thyroid nodules among infants diagnosed with congenital hypothyroidism. METHODS: A retrospective study of 660 infants (374 males, 286 females) diagnosed with congenital hypothyroidism was carried out at the Pediatric Endocrine Clinic in Soonchunhyang University Hospital, Korea, between May 2003 and February 2013. The average age at diagnosis was 1.16±1.68 months. RESULTS: Of the 28 patients (4.2%) with thyroid nodules, 17 (2.6%) had cystic thyroid nodules and 11 (1.6%) had solid thyroid nodules. There were no significant differences in gender or age between congenital hypothyroidism patients who hadthyroid nodules and those who did not. All nodules were asymptomatic. The average age at diagnosis of congenital hypothyroidism with nodules was 1.42±1.39 months. All detected nodules measured less than 1 cm in diameter. Twenty-two of the 28 infants (78.6%) had only one nodule, while multiple nodules were found in 6 infants (21.4%). Of the 28 infants diagnosed with nodules, 16 underwent thyroid ultrasonography during follow-up and 8 of them (50%) showed no signs of nodules at thyroid ultrasonography. CONCLUSION: The prevalence of thyroid nodules in infants with congenital hypothyroidism was 4.2%. Most thyroid nodules were small in size and benign, disappearing during follow-up observation. We therefore conclude that thyroid nodules in infants with congenital hypothyroidism can simply be observed and do not require direct treatment. The Korean Pediatric Society 2014-02 2014-02-24 /pmc/articles/PMC3965800/ /pubmed/24678333 http://dx.doi.org/10.3345/kjp.2014.57.2.85 Text en Copyright © 2014 by The Korean Pediatric Society http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Youn, Seo Young Lee, Jeong Ho Chang, Yun-Woo Lee, Dong Hwan Characteristics of thyroid nodules in infant with congenital hypothyroidism |
title | Characteristics of thyroid nodules in infant with congenital hypothyroidism |
title_full | Characteristics of thyroid nodules in infant with congenital hypothyroidism |
title_fullStr | Characteristics of thyroid nodules in infant with congenital hypothyroidism |
title_full_unstemmed | Characteristics of thyroid nodules in infant with congenital hypothyroidism |
title_short | Characteristics of thyroid nodules in infant with congenital hypothyroidism |
title_sort | characteristics of thyroid nodules in infant with congenital hypothyroidism |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965800/ https://www.ncbi.nlm.nih.gov/pubmed/24678333 http://dx.doi.org/10.3345/kjp.2014.57.2.85 |
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