Reelin, an extracellular matrix protein linked to early onset psychiatric diseases, drives postnatal development of the prefrontal cortex via GluN2B-NMDARs and the mTOR pathway

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Defective brain extracellular matrix (ECM) is a factor of vulnerability in various psychiatric diseases such as schizophrenia, depression and autism. The glycoprotein reelin is an essential building block of the brain ECM that modulates neuronal development and participates to the functions of adult...

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Detalles Bibliográficos
Autores principales: Iafrati, J, Orejarena, M J, Lassalle, O, Bouamrane, L, Chavis, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965840/
https://www.ncbi.nlm.nih.gov/pubmed/23752244
http://dx.doi.org/10.1038/mp.2013.66

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