Cargando…
2-Methyl-6-(phenylethynyl) pyridine (MPEP) reverses maze learning and PSD-95 deficits in Fmr1 knock-out mice
Fragile X Syndrome (FXS) is caused by the lack of expression of the fragile X mental retardation protein (FMRP), which results in intellectual disability and other debilitating symptoms including impairment of visual-spatial functioning. FXS is the only single-gene disorder that is highly co-morbid...
Autores principales: | Gandhi, Réno M., Kogan, Cary S., Messier, Claude |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965849/ https://www.ncbi.nlm.nih.gov/pubmed/24701200 http://dx.doi.org/10.3389/fncel.2014.00070 |
Ejemplares similares
-
Visual–spatial learning impairments are associated with hippocampal PSD-95 protein dysregulation in a mouse model of fragile X syndrome
por: Gandhi, Réno M., et al.
Publicado: (2014) -
The effects of the mGluR5 receptor antagonist 6-methyl-2-(phenylethynyl)-pyridine (MPEP) on behavioural responses to nicotine
por: Tronci, Valeria, et al.
Publicado: (2010) -
Utility of the Hebb–Williams Maze Paradigm for Translational Research in Fragile X Syndrome: A Direct Comparison of Mice and Humans
por: Boutet, Isabelle, et al.
Publicado: (2018) -
Chemical shift assignments of the N-terminal domain of PSD95 (PSD95-NT)
por: Zhang, Yonghong, et al.
Publicado: (2021) -
Deficit in Motor Training-Induced Clustering, but Not Stabilization, of New Dendritic Spines in fmr1 Knock-Out Mice
por: Reiner, Benjamin C., et al.
Publicado: (2015)