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Gastric Adenocarcinoma Presenting with Gastric Outlet Obstruction in a Child

Gastric carcinoma is extremely rare in children representing only 0.05% of all gastrointestinal malignancies. Here, we report the first pediatric case of gastric cancer presenting with gastric outlet obstruction. Upper endoscopy revealed a markedly thickened antral mucosa occluding the pylorus and a...

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Autores principales: Al-Hussaini, Abdulrahman, AlGhamdi, Salem, Alsaaran, Rasha, Al-Kasim, Fawaz, Habib, Zakaria, Ourfali, Nouri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965945/
https://www.ncbi.nlm.nih.gov/pubmed/24707411
http://dx.doi.org/10.1155/2014/527471
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author Al-Hussaini, Abdulrahman
AlGhamdi, Salem
Alsaaran, Rasha
Al-Kasim, Fawaz
Habib, Zakaria
Ourfali, Nouri
author_facet Al-Hussaini, Abdulrahman
AlGhamdi, Salem
Alsaaran, Rasha
Al-Kasim, Fawaz
Habib, Zakaria
Ourfali, Nouri
author_sort Al-Hussaini, Abdulrahman
collection PubMed
description Gastric carcinoma is extremely rare in children representing only 0.05% of all gastrointestinal malignancies. Here, we report the first pediatric case of gastric cancer presenting with gastric outlet obstruction. Upper endoscopy revealed a markedly thickened antral mucosa occluding the pylorus and a clean base ulcer 1.5 cm × 2 cm at the lesser curvature of the stomach. The narrowed antrum and pylorus underwent balloon dilation, and biopsy from the antrum showed evidence of Helicobacter pylori gastritis. The biopsy taken from the edge of the gastric ulcer demonstrated signet-ring-cell type infiltrate consistent with gastric adenocarcinoma. At laparotomy, there were metastases to the liver, head of pancreas, and mesenteric lymph nodes. Therefore, the gastric carcinoma was deemed unresectable. The patient died few months after initiation of chemotherapy due to advanced malignancy. In conclusion, this case report underscores the possibility of gastric adenocarcinoma occurring in children and presenting with gastric outlet obstruction.
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spelling pubmed-39659452014-04-06 Gastric Adenocarcinoma Presenting with Gastric Outlet Obstruction in a Child Al-Hussaini, Abdulrahman AlGhamdi, Salem Alsaaran, Rasha Al-Kasim, Fawaz Habib, Zakaria Ourfali, Nouri Case Rep Gastrointest Med Case Report Gastric carcinoma is extremely rare in children representing only 0.05% of all gastrointestinal malignancies. Here, we report the first pediatric case of gastric cancer presenting with gastric outlet obstruction. Upper endoscopy revealed a markedly thickened antral mucosa occluding the pylorus and a clean base ulcer 1.5 cm × 2 cm at the lesser curvature of the stomach. The narrowed antrum and pylorus underwent balloon dilation, and biopsy from the antrum showed evidence of Helicobacter pylori gastritis. The biopsy taken from the edge of the gastric ulcer demonstrated signet-ring-cell type infiltrate consistent with gastric adenocarcinoma. At laparotomy, there were metastases to the liver, head of pancreas, and mesenteric lymph nodes. Therefore, the gastric carcinoma was deemed unresectable. The patient died few months after initiation of chemotherapy due to advanced malignancy. In conclusion, this case report underscores the possibility of gastric adenocarcinoma occurring in children and presenting with gastric outlet obstruction. Hindawi Publishing Corporation 2014 2014-01-14 /pmc/articles/PMC3965945/ /pubmed/24707411 http://dx.doi.org/10.1155/2014/527471 Text en Copyright © 2014 Abdulrahman Al-Hussaini et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Al-Hussaini, Abdulrahman
AlGhamdi, Salem
Alsaaran, Rasha
Al-Kasim, Fawaz
Habib, Zakaria
Ourfali, Nouri
Gastric Adenocarcinoma Presenting with Gastric Outlet Obstruction in a Child
title Gastric Adenocarcinoma Presenting with Gastric Outlet Obstruction in a Child
title_full Gastric Adenocarcinoma Presenting with Gastric Outlet Obstruction in a Child
title_fullStr Gastric Adenocarcinoma Presenting with Gastric Outlet Obstruction in a Child
title_full_unstemmed Gastric Adenocarcinoma Presenting with Gastric Outlet Obstruction in a Child
title_short Gastric Adenocarcinoma Presenting with Gastric Outlet Obstruction in a Child
title_sort gastric adenocarcinoma presenting with gastric outlet obstruction in a child
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965945/
https://www.ncbi.nlm.nih.gov/pubmed/24707411
http://dx.doi.org/10.1155/2014/527471
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