Cargando…

Cyclodextrin and Polyethylenimine Functionalized Mesoporous Silica Nanoparticles for Delivery of siRNA Cancer Therapeutics

Effective delivery holds the key to successful in vivo application of therapeutic small interfering RNA (siRNA). In this work, we have developed a universal siRNA carrier consisting of a mesoporous silica nanoparticle (MSNP) functionalized with cyclodextrin-grafted polyethylenimine (CP). CP provides...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shen, Jianliang, Kim, Han-Cheon, Su, Hua, Wang, Feng, Wolfram, Joy, Kirui, Dickson, Mai, Junhua, Mu, Chaofeng, Ji, Liang-Nian, Mao, Zong-Wan, Shen, Haifa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2014
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966054/ https://www.ncbi.nlm.nih.gov/pubmed/24672582 http://dx.doi.org/10.7150/thno.8263

Ejemplares similares

Low-weight polyethylenimine cross-linked 2-hydroxypopyl-β-cyclodextrin and folic acid as an efficient and nontoxic siRNA carrier for gene silencing and tumor inhibition by VEGF siRNA
por: Li, Jin-Ming, et al.
Publicado: (2013)

Characterization of modified mesoporous silica nanoparticles as vectors for siRNA delivery
por: Slita, Anna, et al.
Publicado: (2018)

Reversal of multidrug resistance in MCF-7/Adr cells by codelivery of doxorubicin and BCL2 siRNA using a folic acid-conjugated polyethylenimine hydroxypropyl-β-cyclodextrin nanocarrier
por: Li, Jin-Ming, et al.
Publicado: (2015)

High-Capacity Mesoporous Silica Nanocarriers of siRNA for Applications in Retinal Delivery
por: Ultimo, Amelia, et al.
Publicado: (2023)

Recent Advances in Mesoporous Silica Nanoparticles Delivering siRNA for Cancer Treatment
por: Xie, Xiaowei, et al.
Publicado: (2023)

Integration of Polylactide into Polyethylenimine Facilitates the Safe and Effective Intracellular siRNA Delivery
por: Ding, Guo-Bin, et al.
Publicado: (2020)

Hydroxyethyl substituted linear polyethylenimine for safe and efficient delivery of siRNA therapeutics
por: Patil, Sushilkumar, et al.
Publicado: (2018)

Targeting HPV‐infected cervical cancer cells with PEGylated liposomes encapsulating siRNA and the role of siRNA complexation with polyethylenimine
por: Levine, Rachel M., et al.
Publicado: (2016)

Biofunctionalized Decellularized Tissue-Engineered Heart Valve with Mesoporous Silica Nanoparticles for Controlled Release of VEGF and RunX2-siRNA against Calcification
por: Yu, Wenpeng, et al.
Publicado: (2023)

Imaging Intracellular Drug/siRNA Co-Delivery by Self-Assembly Cross-Linked Polyethylenimine with Fluorescent Core-Shell Silica Nanoparticles
por: Zhang, Ruirui, et al.
Publicado: (2022)

Cyclodextrin-assisted synthesis of tailored mesoporous silica nanoparticles
por: Topuz, Fuat, et al.
Publicado: (2018)

Lyophilization and stability of antibody-conjugated mesoporous silica nanoparticle with cationic polymer and PEG for siRNA delivery
por: Ngamcherdtrakul, Worapol, et al.
Publicado: (2018)

Mesoporous silica-coated silver nanoparticles as ciprofloxacin/siRNA carriers for accelerated infected wound healing
por: Liu, Qiqi, et al.
Publicado: (2022)

Polymeric Nanoparticles Based on Tyrosine-Modified, Low Molecular Weight Polyethylenimines for siRNA Delivery
por: Ewe, Alexander, et al.
Publicado: (2019)

Polyethylenimine-Conjugated Hydroxyethyl Cellulose for Doxorubicin/Bcl-2 siRNA Co-Delivery Systems
por: Park, Jiwon, et al.
Publicado: (2023)

Transient Mild Hyperthermia Induces E-selectin Mediated Localization of Mesoporous Silicon Vectors in Solid Tumors
por: Kirui, Dickson K., et al.
Publicado: (2014)

Effective Non-Viral Delivery of siRNA to Acute Myeloid Leukemia Cells with Lipid-Substituted Polyethylenimines
por: Landry, Breanne, et al.
Publicado: (2012)

Enhanced Gene Silencing through Human Serum Albumin-Mediated Delivery of Polyethylenimine-siRNA Polyplexes
por: Nicolì, Elena, et al.
Publicado: (2015)

Targeting Cell Cycle Proteins in Breast Cancer Cells with siRNA by Using Lipid-Substituted Polyethylenimines
por: Parmar, Manoj B., et al.
Publicado: (2015)

Targeted Delivery of siRNA to Transferrin Receptor Overexpressing Tumor Cells via Peptide Modified Polyethylenimine
por: Xie, Yuran, et al.
Publicado: (2016)

Polyethylenimine‐grafted mesoporous silica nanocarriers markedly enhance the bactericidal effect of curcumin against Staphylococcus aureus biofilm
por: Pamukçu, Ayşenur, et al.
Publicado: (2022)

Codelivery of doxorubicin and MDR1-siRNA by mesoporous silica nanoparticles-polymerpolyethylenimine to improve oral squamous carcinoma treatment
por: Wang, Dandan, et al.
Publicado: (2017)

Branched polyethylenimine-grafted-carboxymethyl chitosan copolymer enhances the delivery of pDNA or siRNA in vitro and in vivo
por: Park, Seong-Cheol, et al.
Publicado: (2013)

Superparamagnetic iron oxide nanoparticles modified with polyethylenimine and galactose for siRNA targeted delivery in hepatocellular carcinoma therapy
por: Yang, Zhen, et al.
Publicado: (2018)

Polyethylenimine Nanoparticle-Mediated siRNA Delivery to Reduce α-Synuclein Expression in a Model of Parkinson’s Disease
por: Helmschrodt, Christin, et al.
Publicado: (2017)

Inhibition of Tumor Growth via Systemic siRNA Delivery Using Reducible Bile Acid-Conjugated Polyethylenimine
por: Yin, Yue, et al.
Publicado: (2018)

Tyrosine-Modification of Polypropylenimine (PPI) and Polyethylenimine (PEI) Strongly Improves Efficacy of siRNA-Mediated Gene Knockdown
por: Noske, Sandra, et al.
Publicado: (2020)

cRGD peptide-conjugated polyethylenimine-based lipid nanoparticle for intracellular delivery of siRNA in hepatocarcinoma therapy
por: Yang, Shuang, et al.
Publicado: (2021)

Cross-linked polyethylenimine–tripolyphosphate nanoparticles for gene delivery
por: Huang, Xianzhang, et al.
Publicado: (2014)

Stimuli-Responsive Mesoporous Silica NPs as Non-viral Dual siRNA/Chemotherapy Carriers for Triple Negative Breast Cancer
por: Darvishi, Behrad, et al.
Publicado: (2017)

Tumour-Targeted and Redox-Responsive Mesoporous Silica Nanoparticles for Controlled Release of Doxorubicin and an siRNA Against Metastatic Breast Cancer
por: Zhuang, Jialang, et al.
Publicado: (2021)

siRNA delivery using intelligent chitosan-capped mesoporous silica nanoparticles for overcoming multidrug resistance in malignant carcinoma cells
por: Heidari, Razieh, et al.
Publicado: (2021)

Codelivery of Doxorubicin and MDR1-siRNA by Mesoporous Silica Nanoparticles-Polymerpolyethylenimine to Improve Oral Squamous Carcinoma Treatment [Corrigendum]
Publicado: (2021)

Overcoming the non-kinetic activity of EGFR1 using multi-functionalized mesoporous silica nanocarrier for in vitro delivery of siRNA
por: Parnian, Javad, et al.
Publicado: (2022)

Nischarin-siRNA delivered by polyethylenimine-alginate nanoparticles accelerates motor function recovery after spinal cord injury
por: Ding, Yue-min, et al.
Publicado: (2017)

Stimuli-responsive hybrid nanocarriers developed by controllable integration of hyperbranched PEI with mesoporous silica nanoparticles for sustained intracellular siRNA delivery
por: Prabhakar, Neeraj, et al.
Publicado: (2016)

Tumour-Targeted and Redox-Responsive Mesoporous Silica Nanoparticles for Controlled Release of Doxorubicin and an siRNA Against Metastatic Breast Cancer [Retraction]
Publicado: (2022)

Visible-light-triggered supramolecular valves based on β-cyclodextrin-modified mesoporous silica nanoparticles for controlled drug release
por: Bian, Qing, et al.
Publicado: (2019)

Potential Use of Polyamidoamine Dendrimer Conjugates with Cyclodextrins as Novel Carriers for siRNA
por: Arima, Hidetoshi, et al.
Publicado: (2011)

Tetraethylenepentamine-Coated β Cyclodextrin Nanoparticles for Dual DNA and siRNA Delivery
por: Liu, Chi-Hsien, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_55ap59h1c18nc3pbr3p6ddr4go