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NANOG Is Multiply Phosphorylated and Directly Modified by ERK2 and CDK1 In Vitro

NANOG is a divergent homeobox protein and a core component of the transcriptional circuitry that sustains pluripotency and self-renewal. Although NANOG has been extensively studied on the transcriptional level, little is known regarding its posttranslational regulation, likely due to its low abundan...

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Detalles Bibliográficos
Autores principales: Brumbaugh, Justin, Russell, Jason D., Yu, Pengzhi, Westphall, Michael S., Coon, Joshua J., Thomson, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966117/
https://www.ncbi.nlm.nih.gov/pubmed/24678451
http://dx.doi.org/10.1016/j.stemcr.2013.12.005