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Preliminary assessment of nasopharyngeal carcinoma incidence in the Philippines: a second look at published data from four centers

In endemic regions such as southern China and Southeast Asia, the annual incidence of nasopharyngeal carcinoma (NPC) ranges from 3 to 30 per 100,000. In the Philippines, the estimated incidence in 2010 was 1.2 per 100,000. However, this rate is based on data collected from registries covering only t...

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Autores principales: Sarmiento, Mario Paulus Cesar B., Mejia, Michael Benedict A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sun Yat-sen University Cancer Center 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966143/
https://www.ncbi.nlm.nih.gov/pubmed/23958058
http://dx.doi.org/10.5732/cjc.013.10010
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author Sarmiento, Mario Paulus Cesar B.
Mejia, Michael Benedict A.
author_facet Sarmiento, Mario Paulus Cesar B.
Mejia, Michael Benedict A.
author_sort Sarmiento, Mario Paulus Cesar B.
collection PubMed
description In endemic regions such as southern China and Southeast Asia, the annual incidence of nasopharyngeal carcinoma (NPC) ranges from 3 to 30 per 100,000. In the Philippines, the estimated incidence in 2010 was 1.2 per 100,000. However, this rate is based on data collected from registries covering only two regions in the country. Here, we report the findings from our study to better approximate the incidence of NPC in the Philippines. Between September 1, 2011 and August 31, 2012, data were collected from 49 patients from 4 different institutions—University of Santo Tomas, Makati Medical Center, Philippine Oncology Center Corporation, and Cardinal Santos Memorial Medical Center—using a NPC screening questionnaire. Crude incidence was 0.09 per 100,000. Age-standardized incidences using Segi and WHO standards were 2.08 and 1.79 per 100,000, respectively. Of the 49 patients, 31 were males and 18 were females, and 71% of patients were between 30 and 59 years old. WHO types II and III represented 22% and 78% of the subjects, respectively, and 75.5% of cases were locally advanced (stages III–IVB). Although the age-standardized incidence from the 4 institutions was numerically higher than the published age-standardized incidence (2.07 per 100,000 vs. 1.2 per 100,000), two-proportion z-test showed no significant difference between them (P = 0.68). A more concerted effort is needed for a better approximation of the country's NPC disease burden.
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spelling pubmed-39661432014-03-26 Preliminary assessment of nasopharyngeal carcinoma incidence in the Philippines: a second look at published data from four centers Sarmiento, Mario Paulus Cesar B. Mejia, Michael Benedict A. Chin J Cancer Original Article In endemic regions such as southern China and Southeast Asia, the annual incidence of nasopharyngeal carcinoma (NPC) ranges from 3 to 30 per 100,000. In the Philippines, the estimated incidence in 2010 was 1.2 per 100,000. However, this rate is based on data collected from registries covering only two regions in the country. Here, we report the findings from our study to better approximate the incidence of NPC in the Philippines. Between September 1, 2011 and August 31, 2012, data were collected from 49 patients from 4 different institutions—University of Santo Tomas, Makati Medical Center, Philippine Oncology Center Corporation, and Cardinal Santos Memorial Medical Center—using a NPC screening questionnaire. Crude incidence was 0.09 per 100,000. Age-standardized incidences using Segi and WHO standards were 2.08 and 1.79 per 100,000, respectively. Of the 49 patients, 31 were males and 18 were females, and 71% of patients were between 30 and 59 years old. WHO types II and III represented 22% and 78% of the subjects, respectively, and 75.5% of cases were locally advanced (stages III–IVB). Although the age-standardized incidence from the 4 institutions was numerically higher than the published age-standardized incidence (2.07 per 100,000 vs. 1.2 per 100,000), two-proportion z-test showed no significant difference between them (P = 0.68). A more concerted effort is needed for a better approximation of the country's NPC disease burden. Sun Yat-sen University Cancer Center 2014-03 /pmc/articles/PMC3966143/ /pubmed/23958058 http://dx.doi.org/10.5732/cjc.013.10010 Text en Chinese Journal of Cancer http://creativecommons.org/licenses/by-nc-sa/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License, which allows readers to alter, transform, or build upon the article and then distribute the resulting work under the same or similar license to this one. The work must be attributed back to the original author and commercial use is not permitted without specific permission.
spellingShingle Original Article
Sarmiento, Mario Paulus Cesar B.
Mejia, Michael Benedict A.
Preliminary assessment of nasopharyngeal carcinoma incidence in the Philippines: a second look at published data from four centers
title Preliminary assessment of nasopharyngeal carcinoma incidence in the Philippines: a second look at published data from four centers
title_full Preliminary assessment of nasopharyngeal carcinoma incidence in the Philippines: a second look at published data from four centers
title_fullStr Preliminary assessment of nasopharyngeal carcinoma incidence in the Philippines: a second look at published data from four centers
title_full_unstemmed Preliminary assessment of nasopharyngeal carcinoma incidence in the Philippines: a second look at published data from four centers
title_short Preliminary assessment of nasopharyngeal carcinoma incidence in the Philippines: a second look at published data from four centers
title_sort preliminary assessment of nasopharyngeal carcinoma incidence in the philippines: a second look at published data from four centers
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966143/
https://www.ncbi.nlm.nih.gov/pubmed/23958058
http://dx.doi.org/10.5732/cjc.013.10010
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