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PAH clearance after renal ischemia and reperfusion is a function of impaired expression of basolateral Oat1 and Oat3

Determination of renal plasma flow (RPF) by para‐aminohippurate (PAH) clearance leads to gross underestimation of this respective parameter due to impaired renal extraction of PAH after renal ischemia and reperfusion injury. However, no mechanistic explanation for this phenomenon is available. Based...

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Detalles Bibliográficos
Autores principales: Bischoff, Ariane, Bucher, Michael, Gekle, Michael, Sauvant, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966241/
https://www.ncbi.nlm.nih.gov/pubmed/24744908
http://dx.doi.org/10.1002/phy2.243