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The Interplay of Reovirus with Autophagy

Autophagy participates in multiple fundamental physiological processes, including survival, differentiation, development, and cellular homeostasis. It eliminates cytoplasmic protein aggregates and damaged organelles by triggering a series of events: sequestering the protein substrates into double-me...

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Detalles Bibliográficos
Autores principales: Chiu, Hung-Chuan, Richart, Sarah, Lin, Fong-Yuan, Hsu, Wei-Li, Liu, Hung-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966329/
https://www.ncbi.nlm.nih.gov/pubmed/24711994
http://dx.doi.org/10.1155/2014/483657
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author Chiu, Hung-Chuan
Richart, Sarah
Lin, Fong-Yuan
Hsu, Wei-Li
Liu, Hung-Jen
author_facet Chiu, Hung-Chuan
Richart, Sarah
Lin, Fong-Yuan
Hsu, Wei-Li
Liu, Hung-Jen
author_sort Chiu, Hung-Chuan
collection PubMed
description Autophagy participates in multiple fundamental physiological processes, including survival, differentiation, development, and cellular homeostasis. It eliminates cytoplasmic protein aggregates and damaged organelles by triggering a series of events: sequestering the protein substrates into double-membrane vesicles, fusing the vesicles with lysosomes, and then degrading the autophagic contents. This degradation pathway is also involved in various disorders, for instance, cancers and infectious diseases. This paper provides an overview of modulation of autophagy in the course of reovirus infection and also the interplay of autophagy and reovirus.
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spelling pubmed-39663292014-04-07 The Interplay of Reovirus with Autophagy Chiu, Hung-Chuan Richart, Sarah Lin, Fong-Yuan Hsu, Wei-Li Liu, Hung-Jen Biomed Res Int Review Article Autophagy participates in multiple fundamental physiological processes, including survival, differentiation, development, and cellular homeostasis. It eliminates cytoplasmic protein aggregates and damaged organelles by triggering a series of events: sequestering the protein substrates into double-membrane vesicles, fusing the vesicles with lysosomes, and then degrading the autophagic contents. This degradation pathway is also involved in various disorders, for instance, cancers and infectious diseases. This paper provides an overview of modulation of autophagy in the course of reovirus infection and also the interplay of autophagy and reovirus. Hindawi Publishing Corporation 2014 2014-03-10 /pmc/articles/PMC3966329/ /pubmed/24711994 http://dx.doi.org/10.1155/2014/483657 Text en Copyright © 2014 Hung-Chuan Chiu et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Chiu, Hung-Chuan
Richart, Sarah
Lin, Fong-Yuan
Hsu, Wei-Li
Liu, Hung-Jen
The Interplay of Reovirus with Autophagy
title The Interplay of Reovirus with Autophagy
title_full The Interplay of Reovirus with Autophagy
title_fullStr The Interplay of Reovirus with Autophagy
title_full_unstemmed The Interplay of Reovirus with Autophagy
title_short The Interplay of Reovirus with Autophagy
title_sort interplay of reovirus with autophagy
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966329/
https://www.ncbi.nlm.nih.gov/pubmed/24711994
http://dx.doi.org/10.1155/2014/483657
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