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PHOSPHOLIPASE D (PLD) DRIVES CELL INVASION, TUMOR GROWTH AND METASTASIS IN A HUMAN BREAST CANCER XENOGRAPH MODEL

Breast cancer is one of the most common malignancies in human females in the world. One protein that has elevated enzymatic lipase activity in breast cancers in vitro is phospholipase D (PLD), which is also involved in cell migration. We demonstrate that the PLD2 isoform, which was analyzed directly...

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Detalles Bibliográficos
Autores principales: Henkels, Karen M., Boivin, Gregory P., Dudley, Emily S., Berberich, Steven J., Gomez-Cambronero, Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966651/
https://www.ncbi.nlm.nih.gov/pubmed/23752189
http://dx.doi.org/10.1038/onc.2013.207