Quantification of Pancreatic Cancer Proteome and Phosphorylome: Indicates Molecular Events Likely Contributing to Cancer and Activity of Drug Targets

OBJECTIVE: LC-MS/MS phospho-proteomics is an essential technology to help unravel the complex molecular events that lead to and propagate cancer. We have developed a global phospho-proteomic workflow to determine activity of signaling pathways and drug targets in pancreatic cancer tissue for clinica...

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Detalles Bibliográficos
Autores principales: Britton, David, Zen, Yoh, Quaglia, Alberto, Selzer, Stefan, Mitra, Vikram, Lößner, Christopher, Jung, Stephan, Böhm, Gitte, Schmid, Peter, Prefot, Petra, Hoehle, Claudia, Koncarevic, Sasa, Gee, Julia, Nicholson, Robert, Ward, Malcolm, Castellano, Leandro, Stebbing, Justin, Zucht, Hans Dieter, Sarker, Debashis, Heaton, Nigel, Pike, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966770/
https://www.ncbi.nlm.nih.gov/pubmed/24670416
http://dx.doi.org/10.1371/journal.pone.0090948

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