Cargando…

Glycan Masking of Hemagglutinin for Adenovirus Vector and Recombinant Protein Immunizations Elicits Broadly Neutralizing Antibodies against H5N1 Avian Influenza Viruses

The highly pathogenic avian influenza (HPAI) H5N1 virus, a known trigger of diseases in poultry and humans, is perceived as a serious threat to public health. There is a clear need for a broadly protective H5N1 vaccine or vaccines for inducing neutralizing antibodies against multiple clades/subclade...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lin, Shih-Chang, Liu, Wen-Chun, Jan, Jia-Tsrong, Wu, Suh-Chin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966833/ https://www.ncbi.nlm.nih.gov/pubmed/24671139 http://dx.doi.org/10.1371/journal.pone.0092822

Ejemplares similares

Site-Specific Glycan-Masking/Unmasking Hemagglutinin Antigen Design to Elicit Broadly Neutralizing and Stem-Binding Antibodies Against Highly Pathogenic Avian Influenza H5N1 Virus Infections
por: Chen, Ting-Hsuan, et al.
Publicado: (2021)

Different Immunity Elicited by Recombinant H5N1 Hemagglutinin Proteins Containing Pauci-Mannose, High-Mannose, or Complex Type N-Glycans
por: Lin, Shih-Chang, et al.
Publicado: (2013)

Glycan Masking of Epitopes in the NTD and RBD of the Spike Protein Elicits Broadly Neutralizing Antibodies Against SARS-CoV-2 Variants
por: Lin, Wei-Shuo, et al.
Publicado: (2021)

Highly Pathogenic Avian Influenza H5 Hemagglutinin Fused with the A Subunit of Type IIb Escherichia coli Heat Labile Enterotoxin Elicited Protective Immunity and Neutralization by Intranasal Immunization in Mouse and Chicken Models
por: Tang, Neos, et al.
Publicado: (2019)

Autoreactivity profiles of influenza hemagglutinin broadly neutralizing antibodies
por: Bajic, Goran, et al.
Publicado: (2019)

A broadly neutralizing human monoclonal antibody against the hemagglutinin of avian influenza virus H7N9
por: Li, Jingxin, et al.
Publicado: (2022)

Administration of Multivalent Influenza Virus Recombinant Hemagglutinin Vaccine in Combination-Adjuvant Elicits Broad Reactivity Beyond the Vaccine Components
por: Hernandez-Davies, Jenny E., et al.
Publicado: (2021)

Baculovirus Displaying Hemagglutinin Elicits Broad Cross-Protection against Influenza in Mice
por: Sim, Sang-Hee, et al.
Publicado: (2016)

Glycan repositioning of influenza hemagglutinin stem facilitates the elicitation of protective cross-group antibody responses
por: Boyoglu-Barnum, Seyhan, et al.
Publicado: (2020)

Broad cross-reactive IgG responses elicited by adjuvanted vaccination with recombinant influenza hemagglutinin (rHA) in ferrets and mice
por: Wang, Jiong, et al.
Publicado: (2018)

Erratum: Administration of Multivalent Influenza Virus Recombinant Hemagglutinin Vaccine in Combination-Adjuvant Elicits Broad Reactivity Beyond the Vaccine Components
Publicado: (2021)

Influenza Hemagglutinin Nanoparticle Vaccine Elicits Broadly Neutralizing Antibodies against Structurally Distinct Domains of H3N2 HA
por: Portnoff, Alyse D., et al.
Publicado: (2020)

A computationally optimized broadly reactive hemagglutinin vaccine elicits neutralizing antibodies against influenza B viruses from both lineages
por: Carlock, Michael A., et al.
Publicado: (2023)

In vitro evolution of an influenza broadly neutralizing antibody is modulated by hemagglutinin receptor specificity
por: Wu, Nicholas C., et al.
Publicado: (2017)

Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses
por: Kanekiyo, Masaru, et al.
Publicado: (2019)

Recombinant Trimeric HA Protein Immunogenicity of H5N1 Avian Influenza Viruses and Their Combined Use with Inactivated or Adenovirus Vaccines
por: Lin, Shih-Chang, et al.
Publicado: (2011)

Use of PELC/CpG Adjuvant for Intranasal Immunization with Recombinant Hemagglutinin to Develop H7N9 Mucosal Vaccine
por: Chen, Ting-Hsuan, et al.
Publicado: (2020)

Fc-Based Recombinant Henipavirus Vaccines Elicit Broad Neutralizing Antibody Responses in Mice
por: Li, Yaohui, et al.
Publicado: (2020)

Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability
por: Dubrovskaya, Viktoriya, et al.
Publicado: (2019)

Cross-reactivity of glycan-reactive HIV-1 broadly neutralizing antibodies with parasite glycans
por: Huettner, Isabella, et al.
Publicado: (2022)

Conserved Influenza Hemagglutinin, Neuraminidase and Matrix Peptides Adjuvanted with ALFQ Induce Broadly Neutralizing Antibodies
por: Sei, Clara J., et al.
Publicado: (2021)

Human Influenza Virus Hemagglutinins Contain Conserved Oligomannose N-Linked Glycans Allowing Potent Neutralization by Lectins
por: Thompson, Andrew J., et al.
Publicado: (2020)

Recombinant influenza H7 hemagglutinins induce lower neutralizing antibody titers in mice than do seasonal hemagglutinins
por: Blanchfield, Kristy, et al.
Publicado: (2014)

The HIV glycan shield as a target for broadly neutralizing antibodies
por: Doores, Katie J.
Publicado: (2015)

Characterization of the immune responses elicited by baculovirus-based vector vaccines against influenza virus hemagglutinin
por: Hu, Zhi-peng, et al.
Publicado: (2012)

Hemagglutinin stalk-based monoclonal antibody elicits broadly reactivity against group 1 influenza A virus
por: Huang, Jingjin, et al.
Publicado: (2020)

An Adenovirus-Vectored Influenza Vaccine Induces Durable Cross-Protective Hemagglutinin Stalk Antibody Responses in Mice
por: Kim, Eun Hye, et al.
Publicado: (2017)

Antigenic Characterization of Recombinant Hemagglutinin Proteins Derived from Different Avian Influenza Virus Subtypes
por: Mueller, Matthias, et al.
Publicado: (2010)

Hemagglutinin-Specific Non-neutralizing Antibody Is Essential for Protection Provided by Inactivated and Viral-Vectored H7N9 Avian Influenza Vaccines in Chickens
por: Hu, Zenglei, et al.
Publicado: (2020)

Mechanism of Glycan Receptor Recognition and Specificity Switch for Avian, Swine, and Human Adapted Influenza Virus Hemagglutinins: A Molecular Dynamics Perspective
por: Newhouse, E. Irene, et al.
Publicado: (2009)

Broadly-Reactive Neutralizing and Non-neutralizing Antibodies Directed against the H7 Influenza Virus Hemagglutinin Reveal Divergent Mechanisms of Protection
por: Tan, Gene S., et al.
Publicado: (2016)

Isolation of Recombinant Phage Antibodies Targeting the Hemagglutinin Cleavage Site of Highly Pathogenic Avian Influenza Virus
por: Dong, Jinhua, et al.
Publicado: (2013)

Construction of recombinant baculoviruses expressing hemagglutinin of H5N1 avian influenza and research on the immunogenicity
por: Ge, Jingping, et al.
Publicado: (2016)

An Adenovirus Vector Incorporating Carbohydrate Binding Domains Utilizes Glycans for Gene Transfer
por: Kim, Julius W., et al.
Publicado: (2013)

Broadly Reactive H2 Hemagglutinin Vaccines Elicit Cross-Reactive Antibodies in Ferrets Preimmune to Seasonal Influenza A Viruses
por: Reneer, Z. Beau, et al.
Publicado: (2021)

Chimeric hemagglutinin split vaccines elicit broadly cross-reactive antibodies and protection against group 2 influenza viruses in mice
por: Puente-Massaguer, Eduard, et al.
Publicado: (2023)

Recombinant hemagglutinin protein and DNA-RNA-combined nucleic acid vaccines harbored by yeast elicit protective immunity against H9N2 avian influenza infection
por: Zhang, Huixia, et al.
Publicado: (2023)

Mechanisms of Hemagglutinin Targeted Influenza Virus Neutralization
por: Brandenburg, Boerries, et al.
Publicado: (2013)

Human Influenza A Virus Hemagglutinin Glycan Evolution Follows a Temporal Pattern to a Glycan Limit
por: Altman, Meghan O., et al.
Publicado: (2019)

Designer antigens for elicitation of broadly neutralizing antibodies against HIV
por: Kok, Tuckweng, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_m1loo2ote0tn5haf45av42942d