Lipoxin A4 and Platelet Activating Factor Are Involved in E. coli or LPS-Induced Lung Inflammation in CFTR-Deficient Mice

CFTR (cystic fibrosis transmembrane conductance regulator) is expressed by both neutrophils and platelets. Lack of functional CFTR could lead to severe lung infection and inflammation. Here, we found that mutation of CFTR (F508del) or inhibition of CFTR in mice led to more severe thrombocytopenia, a...

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Detalles Bibliográficos
Autores principales: Wu, Haiya, Yang, Jun, Su, Emily M., Li, Ling, Zhao, Caiqi, Yang, Xi, Gao, Zhaowei, Pan, Mengyao, Sun, Peiyu, Sun, Wei, Jiang, Yiyi, Su, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966846/
https://www.ncbi.nlm.nih.gov/pubmed/24671173
http://dx.doi.org/10.1371/journal.pone.0093003

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