Designing a High-Throughput Somatic Mutation Profiling Panel Specifically for Gynaecological Cancers

Somatic mutations play a major role in tumour initiation and progression. The mutation status of a tumour may predict prognosis and guide targeted therapies. The majority of techniques to study oncogenic mutations require high quality and quantity DNA or are analytically challenging. Mass-spectromet...

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Detalles Bibliográficos
Autores principales: Spaans, Vivian M., Trietsch, Marjolijn D., Crobach, Stijn, Stelloo, Ellen, Kremer, Dennis, Osse, Elisabeth M., Haar, Natalja T. ter., van Eijk, Ronald, Muller, Susanne, van Wezel, Tom, Trimbos, J. Baptist, Bosse, Tjalling, Smit, Vincent T. H. B. M., Fleuren, Gert Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966900/
https://www.ncbi.nlm.nih.gov/pubmed/24671188
http://dx.doi.org/10.1371/journal.pone.0093451

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