Cargando…

Efficacy and Safety of AM-101 in the Treatment of Acute Inner Ear Tinnitus—A Double-Blind, Randomized, Placebo-Controlled Phase II Study

OBJECTIVE: To evaluate the efficacy and safety of intratympanic AM-101 in patients with persistent acute inner ear tinnitus after acute acoustic trauma, idiopathic sudden sensorineural hearing loss (ISSNHL), or acute otitis media. STUDY DESIGN: Prospective, double-blind, randomized, placebo-controll...

Descripción completa

Detalles Bibliográficos
Autores principales:	van de Heyning, Paul, Muehlmeier, Guido, Cox, Tony, Lisowska, Grazyna, Maier, Heinz, Morawski, Krzysztof, Meyer, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2014
Materias:	Sensorineural Hearing Loss & Tinnitus
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966923/ https://www.ncbi.nlm.nih.gov/pubmed/24603353 http://dx.doi.org/10.1097/MAO.0000000000000268

Ejemplares similares

Characteristics and Spontaneous Recovery of Tinnitus Related to Idiopathic Sudden Sensorineural Hearing Loss
por: Mühlmeier, Guido, et al.
Publicado: (2016)

Efficacy and Safety of AM-111 in the Treatment of Acute Unilateral Sudden Deafness—A Double-blind, Randomized, Placebo-controlled Phase 3 Study
por: Staecker, Hinrich, et al.
Publicado: (2019)

Altered Contralateral Auditory Cortical Morphology in Unilateral Sudden Sensorineural Hearing Loss
por: Fan, Wenliang, et al.
Publicado: (2015)

Sudden Sensorineural Hearing Loss in Children: Clinical Characteristics, Etiology, Treatment Outcomes, and Prognostic Factors
por: Lu, Yuqing, et al.
Publicado: (2019)

Serum Bilirubin Level as a Potential Marker for the Hearing Outcome in Severe-Profound Bilateral Sudden Deafness
por: Bing, Dan, et al.
Publicado: (2019)

Awareness, Perceptions, and Literacy Surrounding Hearing Loss and Hearing Rehabilitation Among the Adult Population in the United States
por: Carlson, Matthew L., et al.
Publicado: (2022)

Improved Speech Intelligibility in Subjects With Stable Sensorineural Hearing Loss Following Intratympanic Dosing of FX-322 in a Phase 1b Study
por: McLean, Will J., et al.
Publicado: (2021)

Hearing Health Perceptions and Literacy Among Primary Healthcare Providers in the United States: A National Cross-Sectional Survey
por: Sydlowski, Sarah A., et al.
Publicado: (2022)

Repeated Audiometry After Bacterial Meningitis: Consequences for Future Management
por: Rodenburg-Vlot, Marian B. A., et al.
Publicado: (2018)

Bilateral Sudden Sensorineural Hearing Loss and Intralabyrinthine Hemorrhage in a Patient With COVID-19
por: Chern, Alexander, et al.
Publicado: (2021)

Headache, tinnitus and hearing loss in the international Cohort Study of Mobile Phone Use and Health (COSMOS) in Sweden and Finland
por: Auvinen, Anssi, et al.
Publicado: (2019)

Noise Exposure in Palestinian Workers Without a Diagnosis of Hearing Impairment: Relations to Speech-Perception-in-Noise Difficulties, Tinnitus, and Hyperacusis
por: Shehabi, Adnan M., et al.
Publicado: (2023)

Safety of Repeated-Dose Intratympanic Injections with AM-101 in Acute Inner Ear Tinnitus
por: Staecker, Hinrich, et al.
Publicado: (2017)

Attenuation of Positive Valence in Ratings of Affective Sounds by Tinnitus Patients
por: Szibor, Annett, et al.
Publicado: (2018)

Serial Recall Predicts Vocoded Sentence Recognition Across Spectral Resolutions
por: Bosen, Adam K., et al.
Publicado: (2020)

Computerized Speechreading Training for Deaf Children: A Randomized Controlled Trial
por: Pimperton, Hannah, et al.
Publicado: (2019)

Singing Proficiency of Members of a Choir Formed by Prelingually Deafened Children With Cochlear Implants
por: Yang, Jing, et al.
Publicado: (2019)

A Comparison of Behavioral Methods for Indexing the Auditory Processing of Temporal Fine Structure Cues
por: Hoover, Eric C., et al.
Publicado: (2019)

Development and Validation of Sentences Without Semantic Context to Complement the Basic English Lexicon Sentences
por: O'Neill, Erin R., et al.
Publicado: (2020)

Longitudinal Changes in Auditory and Cognitive Function in Middle-Aged and Older Adults
por: Humes, Larry E.
Publicado: (2021)

A Comparison of the Perceived Hearing Difficulties of Community and Clinical Samples of Older Adults
por: Humes, Larry E., et al.
Publicado: (2021)

Core Values in the Traditional Provision of Hearing Health Care
por: Menon, Katherine N., et al.
Publicado: (2023)

Effortful Listening Despite Correct Responses: The Cost of Mental Repair in Sentence Recognition by Listeners With Cochlear Implants
por: Winn, Matthew B., et al.
Publicado: (2022)

Development and Evaluation of Pediatric Versions of the Vanderbilt Fatigue Scale for Children With Hearing Loss
por: Hornsby, Benjamin W. Y., et al.
Publicado: (2022)

Tinnitus Treatment Using Noninvasive and Minimally Invasive Electric Stimulation: Experimental Design and Feasibility
por: Zeng, Fan-Gang, et al.
Publicado: (2019)

Neuronavigated Versus Non-navigated Repetitive Transcranial Magnetic Stimulation for Chronic Tinnitus: A Randomized Study
por: Sahlsten, Hanna, et al.
Publicado: (2019)

Tinnitus Research: Improvement and Innovation
por: Baguley, David M., et al.
Publicado: (2019)

Diagnostic Criteria for Somatosensory Tinnitus: A Delphi Process and Face-to-Face Meeting to Establish Consensus
por: Michiels, Sarah, et al.
Publicado: (2018)

Why Is Tinnitus a Problem? A Qualitative Analysis of Problems Reported by Tinnitus Patients
por: Watts, Emily J., et al.
Publicado: (2018)

Association Between Subjective Tinnitus and Cervical Spine or Temporomandibular Disorders: A Systematic Review
por: Bousema, E. J., et al.
Publicado: (2018)

Comparison of Amplitude Modulated Sounds and Pure Tones at the Tinnitus Frequency: Residual Tinnitus Suppression and Stimulus Evaluation
por: Neff, Patrick, et al.
Publicado: (2019)

Effects of Tinnitus on Cochlear Implant Programming
por: Pierzycki, Robert H., et al.
Publicado: (2019)

A systematic review of dydrogesterone for the treatment of threatened miscarriage
por: Carp, Howard
Publicado: (2012)

Alleviation of Tinnitus With High-Frequency Stimulation of the Dorsal Cochlear Nucleus: A Rodent Study
por: van Zwieten, Gusta, et al.
Publicado: (2019)

Are Open-Fit Hearing Aids a Possible Alternative to Bone-Anchored Hearing Devices in Patients with Mild to Severe Hearing Loss? A Preliminary Trial
por: Ostevik, Amberley V., et al.
Publicado: (2013)

Variations in the Size and Shape of Human Cochlear Malformation Types
por: Dhanasingh, Anandhan
Publicado: (2019)

The effects of acupuncture on the inner ear originated tinnitus*
por: Rogha, Mehrdad, et al.
Publicado: (2011)

Measuring the Impact of Tinnitus on Aided Listening Effort Using Pupillary Response
por: Juul Jensen, Josefine, et al.
Publicado: (2018)

The COMiT’ID Study: Developing Core Outcome Domains Sets for Clinical Trials of Sound-, Psychology-, and Pharmacology-Based Interventions for Chronic Subjective Tinnitus in Adults
por: Hall, Deborah A., et al.
Publicado: (2018)

Cannabinoids, Inner Ear, Hearing, and Tinnitus: A Neuroimmunological Perspective
por: Perin, Paola, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_5bmf34f5nka21njdh0gahhj4p1