CS1-Specific Chimeric Antigen Receptor (CAR)-Engineered Natural Killer Cells Enhance In Vitro and In Vivo Anti-tumor Activity Against Human Multiple Myeloma

Multiple myeloma (MM) is an incurable hematological malignancy. Chimeric antigen receptor (CAR)-expressing T cells have been demonstrated successful in the clinic to treat B-lymphoid malignancies. However, the potential utility of antigen-specific CAR-engineered natural killer (NK) cells to treat MM...

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Detalles Bibliográficos
Autores principales: Chu, Jianhong, Deng, Youcai, Benson, Don M., He, Shun, Hughes, Tiffany, Zhang, Jianying, Peng, Yong, Mao, Hsiaoyin, Yi, Ling, Ghoshal, Kalpana, He, Xiaoming, Devine, Steven M., Zhang, Xiaoliu, Caligiuri, Michael A., Hofmeister, Craig C., Yu, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967004/
https://www.ncbi.nlm.nih.gov/pubmed/24067492
http://dx.doi.org/10.1038/leu.2013.279

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