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High expression of APAF-1 elevates erythroid apoptosis in iron overload myelodysplastic syndrome

Apoptotic protease-activating factor 1 (APAF-1) is a central component of the intrinsic pathway of apoptosis. Our study aims at searching the role of APAF-1 in iron overload myelodysplastic syndrome (MDS). Erythroid apoptosis rate, mRNA expression levels of APAF-1, and caspase-9 activity were determ...

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Detalles Bibliográficos
Autores principales:	Gu, Shucheng, Zhao, Youshan, Guo, Juan, Xu, Feng, Fei, Chengming, Zhang, Xi, Xiao, Chao, Chang, Chunkang, Li, Xiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Netherlands 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967075/ https://www.ncbi.nlm.nih.gov/pubmed/24142530 http://dx.doi.org/10.1007/s13277-013-1294-x

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