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Chromosome movement in meiosis I prophase of Caenorhabditis elegans
Rapid chromosome movement during prophase of the first meiotic division has been observed in many organisms. It is generally concomitant with formation of the “meiotic chromosome bouquet,” a special chromosome configuration in which one or both chromosome ends attach to the nuclear envelope and beco...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967079/ https://www.ncbi.nlm.nih.gov/pubmed/24036686 http://dx.doi.org/10.1007/s00412-013-0436-7 |
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author | Woglar, Alexander Jantsch, Verena |
author_facet | Woglar, Alexander Jantsch, Verena |
author_sort | Woglar, Alexander |
collection | PubMed |
description | Rapid chromosome movement during prophase of the first meiotic division has been observed in many organisms. It is generally concomitant with formation of the “meiotic chromosome bouquet,” a special chromosome configuration in which one or both chromosome ends attach to the nuclear envelope and become concentrated within a limited area. The precise function of the chromosomal bouquet is still not fully understood. Chromosome mobility is implicated in homologous chromosome pairing, synaptonemal complex formation, recombination, and resolution of chromosome entanglements. The basic mechanistic module through which forces are exerted on chromosomes is widely conserved; however, phenotypic differences have been reported among various model organisms once movement is abrogated. Movements are transmitted to the chromosome ends by the nuclear membrane-bridging SUN/KASH complex and are dependent on cytoskeletal filaments and motor proteins located in the cytoplasm. Here we review the recent findings on chromosome mobility during meiosis in an animal model system: the Caenorhabditis elegans nematode. |
format | Online Article Text |
id | pubmed-3967079 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-39670792014-03-27 Chromosome movement in meiosis I prophase of Caenorhabditis elegans Woglar, Alexander Jantsch, Verena Chromosoma Review Rapid chromosome movement during prophase of the first meiotic division has been observed in many organisms. It is generally concomitant with formation of the “meiotic chromosome bouquet,” a special chromosome configuration in which one or both chromosome ends attach to the nuclear envelope and become concentrated within a limited area. The precise function of the chromosomal bouquet is still not fully understood. Chromosome mobility is implicated in homologous chromosome pairing, synaptonemal complex formation, recombination, and resolution of chromosome entanglements. The basic mechanistic module through which forces are exerted on chromosomes is widely conserved; however, phenotypic differences have been reported among various model organisms once movement is abrogated. Movements are transmitted to the chromosome ends by the nuclear membrane-bridging SUN/KASH complex and are dependent on cytoskeletal filaments and motor proteins located in the cytoplasm. Here we review the recent findings on chromosome mobility during meiosis in an animal model system: the Caenorhabditis elegans nematode. Springer Berlin Heidelberg 2013-09-15 2014 /pmc/articles/PMC3967079/ /pubmed/24036686 http://dx.doi.org/10.1007/s00412-013-0436-7 Text en © The Author(s) 2013 https://creativecommons.org/licenses/by-nc/2.0/ Open Access This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. |
spellingShingle | Review Woglar, Alexander Jantsch, Verena Chromosome movement in meiosis I prophase of Caenorhabditis elegans |
title | Chromosome movement in meiosis I prophase of Caenorhabditis elegans |
title_full | Chromosome movement in meiosis I prophase of Caenorhabditis elegans |
title_fullStr | Chromosome movement in meiosis I prophase of Caenorhabditis elegans |
title_full_unstemmed | Chromosome movement in meiosis I prophase of Caenorhabditis elegans |
title_short | Chromosome movement in meiosis I prophase of Caenorhabditis elegans |
title_sort | chromosome movement in meiosis i prophase of caenorhabditis elegans |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967079/ https://www.ncbi.nlm.nih.gov/pubmed/24036686 http://dx.doi.org/10.1007/s00412-013-0436-7 |
work_keys_str_mv | AT woglaralexander chromosomemovementinmeiosisiprophaseofcaenorhabditiselegans AT jantschverena chromosomemovementinmeiosisiprophaseofcaenorhabditiselegans |