Cargando…

The Cyclin-Dependent Kinase Ortholog pUL97 of Human Cytomegalovirus Interacts with Cyclins

The human cytomegalovirus (HCMV)-encoded protein kinase, pUL97, is considered a cyclin-dependent kinase (CDK) ortholog, due to shared structural and functional characteristics. The primary mechanism of CDK activation is binding to corresponding cyclins, including cyclin T1, which is the usual regula...

Descripción completa

Detalles Bibliográficos
Autores principales:	Graf, Laura, Webel, Rike, Wagner, Sabrina, Hamilton, Stuart T., Rawlinson, William D., Sticht, Heinrich, Marschall, Manfred
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967168/ https://www.ncbi.nlm.nih.gov/pubmed/24351800 http://dx.doi.org/10.3390/v5123213

Ejemplares similares

The Interaction between Cyclin B1 and Cytomegalovirus Protein Kinase pUL97 is Determined by an Active Kinase Domain
por: Steingruber, Mirjam, et al.
Publicado: (2015)

Proteomic Interaction Patterns between Human Cyclins, the Cyclin-Dependent Kinase Ortholog pUL97 and Additional Cytomegalovirus Proteins
por: Steingruber, Mirjam, et al.
Publicado: (2016)

Cytomegalovirus cyclin-dependent kinase ortholog vCDK/pUL97 undergoes regulatory interaction with human cyclin H and CDK7 to codetermine viral replication efficiency
por: Schütz, Martin, et al.
Publicado: (2023)

Functional Relevance of the Interaction between Human Cyclins and the Cytomegalovirus-Encoded CDK-Like Protein Kinase pUL97
por: Schütz, Martin, et al.
Publicado: (2021)

Highly Conserved Interaction Profiles between Clinically Relevant Mutants of the Cytomegalovirus CDK-like Kinase pUL97 and Human Cyclins: Functional Significance of Cyclin H
por: Schütz, Martin, et al.
Publicado: (2022)

Cyclin-Dependent Kinases (CDKs) and the Human Cytomegalovirus-Encoded CDK Ortholog pUL97 Represent Highly Attractive Targets for Synergistic Drug Combinations
por: Wild, Markus, et al.
Publicado: (2022)

Human Cytomegalovirus Nuclear Capsids Associate with the Core Nuclear Egress Complex and the Viral Protein Kinase pUL97
por: Milbradt, Jens, et al.
Publicado: (2018)

The Cytomegalovirus Protein Kinase pUL97: Host Interactions, Regulatory Mechanisms and Antiviral Drug Targeting
por: Steingruber, Mirjam, et al.
Publicado: (2020)

Human Cytomegalovirus Replication Is Strictly Inhibited by siRNAs Targeting UL54, UL97 or UL122/123 Gene Transcripts
por: Hamilton, Stuart T., et al.
Publicado: (2014)

Recombinant Human Cytomegalovirus Expressing an Analog-Sensitive Kinase pUL97 as Novel Tool for Functional Analyses
por: Krämer, Nadine, et al.
Publicado: (2022)

Human cytomegaloviral multifunctional protein kinase pUL97 impairs zebrafish embryonic development and increases mortality
por: Cazorla-Vázquez, Salvador, et al.
Publicado: (2019)

Serine 13 of the human cytomegalovirus viral cyclin-dependent kinase UL97 is required for regulatory protein 14-3-3 binding and UL97 stability
por: Iwahori, Satoko, et al.
Publicado: (2022)

Cyclin A Degradation by Primate Cytomegalovirus Protein pUL21a Counters Its Innate Restriction of Virus Replication
por: Caffarelli, Nicolas, et al.
Publicado: (2013)

New Insights into Human Cytomegalovirus pUL52 Structure
por: Muller, Clotilde, et al.
Publicado: (2021)

The Complex Regulatory Role of Cytomegalovirus Nuclear Egress Protein pUL50 in the Production of Infectious Virus
por: Häge, Sigrun, et al.
Publicado: (2021)

Phenotypical Characterization of the Nuclear Egress of Recombinant Cytomegaloviruses Reveals Defective Replication upon ORF-UL50 Deletion but Not pUL50 Phosphosite Mutation
por: Häge, Sigrun, et al.
Publicado: (2021)

Human cytomegalovirus pUL97 upregulates SOCS3 expression via transcription factor RFX7 in neural progenitor cells
por: Wang, Xian-Zhang, et al.
Publicado: (2023)

Insights into herpesvirus assembly from the structure of the pUL7:pUL51 complex
por: Butt, Benjamin G, et al.
Publicado: (2020)

The Cytomegalovirus protein pUL37×1 targets mitochondria to mediate neuroprotection
por: Hong, Chien Tai, et al.
Publicado: (2016)

The contribution of pUL74 to growth of human cytomegalovirus is masked in the presence of RL13 and UL128 expression
por: Laib Sampaio, Kerstin, et al.
Publicado: (2016)

Human Cytomegalovirus Tegument Protein pUL71 Is Required for Efficient Virion Egress
por: Womack, Andrew, et al.
Publicado: (2010)

Identification of a short sequence in the HCMV terminase pUL56 essential for interaction with pUL89 subunit
por: Ligat, G., et al.
Publicado: (2017)

N-Linked Glycosylation and Expression of Duck Plague Virus pUL10 Promoted by pUL49.5
por: Li, Chunmei, et al.
Publicado: (2023)

Human cytomegalovirus protein pUL36: A dual cell death pathway inhibitor
por: Fletcher-Etherington, Alice, et al.
Publicado: (2020)

Dual Function of the pUL7-pUL51 Tegument Protein Complex in Herpes Simplex Virus 1 Infection
por: Albecka, Anna, et al.
Publicado: (2017)

Human Cytomegalovirus pUL79 Is an Elongation Factor of RNA Polymerase II for Viral Gene Transcription
por: Perng, Yi-Chieh, et al.
Publicado: (2014)

8‐Hydroxy‐1,6‐naphthyridine‐7‐carboxamides as Inhibitors of Human Cytomegalovirus pUL89 Endonuclease
por: Jung, Eunkyung, et al.
Publicado: (2022)

Identification of Small Molecule Inhibitors of Human Cytomegalovirus pUL89 Endonuclease Using Integrated Computational Approaches
por: Almehmadi, Mazen, et al.
Publicado: (2023)

PUL21a-Cyclin A2 Interaction is Required to Protect Human Cytomegalovirus-Infected Cells from the Deleterious Consequences of Mitotic Entry
por: Eifler, Martin, et al.
Publicado: (2014)

The effects of maribavir on the autophosphorylation of ganciclovir resistant mutants of the cytomegalovirus UL97 protein
por: Shannon-Lowe, Claire D, et al.
Publicado: (2010)

Distribution of the CMV glycoprotein gH/gL/gO and gH/gL/pUL128/pUL130/pUL131A complex variants and associated clinical manifestations in infants infected congenitally or postnatally
por: Paradowska, Edyta, et al.
Publicado: (2019)

Human Cytomegalovirus Protein pUL117 Targets the Mini-Chromosome Maintenance Complex and Suppresses Cellular DNA Synthesis
por: Qian, Zhikang, et al.
Publicado: (2010)

Human Cytomegalovirus-Encoded pUL7 Is a Novel CEACAM1-Like Molecule Responsible for Promotion of Angiogenesis
por: MacManiman, Jason D., et al.
Publicado: (2014)

The human cytomegalovirus glycoprotein pUL11 acts via CD45 to induce T cell IL-10 secretion
por: Zischke, Jasmin, et al.
Publicado: (2017)

Full-length human cytomegalovirus terminase pUL89 adopts a two-domain structure specific for DNA packaging
por: Theiß, Janine, et al.
Publicado: (2019)

Assessment of the Human Cytomegalovirus UL97 Gene for Identification of Resistance to Ganciclovir in Iranian Immunosuppressed Patients
por: Keyvani, Hossein, et al.
Publicado: (2016)

Expression and intracellular localization of duck enteritis virus pUL38 protein
por: Xiang, Jun, et al.
Publicado: (2010)

Duck enteritis virus UL21 is a late gene encoding a protein that interacts with pUL16
por: Yang, Linjiang, et al.
Publicado: (2020)

Neutralization of Diverse Human Cytomegalovirus Strains Conferred by Antibodies Targeting Viral gH/gL/pUL128-131 Pentameric Complex
por: Ha, Sha, et al.
Publicado: (2017)

Human Cytomegalovirus pUL11, a CD45 Ligand, Disrupts CD4 T Cell Control of Viral Spread in Epithelial Cells
por: Osanyinlusi, Samuel A., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_c4si7d0a6icicvvf280ftikp68