Spirobisnaphthalenes from the Mangrove-Derived Fungus Rhytidhysteron sp. AS21B

Three new spirobisnaphthalenes (1–3) were isolated from the mangrove-derived fungus Rhytidhysteron sp., together with five known derivatives (4–8). The structures of the compounds were established on the basis of extensive spectroscopic data, and the relative configurations of their stereogenic carb...

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Autores principales: Pudhom, Khanitha, Teerawatananond, Thapong, Chookpaiboon, Supichar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967209/
https://www.ncbi.nlm.nih.gov/pubmed/24663115
http://dx.doi.org/10.3390/md12031271
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author Pudhom, Khanitha
Teerawatananond, Thapong
Chookpaiboon, Supichar
author_facet Pudhom, Khanitha
Teerawatananond, Thapong
Chookpaiboon, Supichar
author_sort Pudhom, Khanitha
collection PubMed
description Three new spirobisnaphthalenes (1–3) were isolated from the mangrove-derived fungus Rhytidhysteron sp., together with five known derivatives (4–8). The structures of the compounds were established on the basis of extensive spectroscopic data, and the relative configurations of their stereogenic carbons were determined by a single-crystal X-ray crystallographic analysis. Compounds 3–5 displayed cytotoxicity against both cancer cell lines, MCF-7 and CaSki, while 2 was active only on CaSKi cells.
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spelling pubmed-39672092014-03-27 Spirobisnaphthalenes from the Mangrove-Derived Fungus Rhytidhysteron sp. AS21B Pudhom, Khanitha Teerawatananond, Thapong Chookpaiboon, Supichar Mar Drugs Communication Three new spirobisnaphthalenes (1–3) were isolated from the mangrove-derived fungus Rhytidhysteron sp., together with five known derivatives (4–8). The structures of the compounds were established on the basis of extensive spectroscopic data, and the relative configurations of their stereogenic carbons were determined by a single-crystal X-ray crystallographic analysis. Compounds 3–5 displayed cytotoxicity against both cancer cell lines, MCF-7 and CaSki, while 2 was active only on CaSKi cells. MDPI 2014-03-06 /pmc/articles/PMC3967209/ /pubmed/24663115 http://dx.doi.org/10.3390/md12031271 Text en © 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Communication
Pudhom, Khanitha
Teerawatananond, Thapong
Chookpaiboon, Supichar
Spirobisnaphthalenes from the Mangrove-Derived Fungus Rhytidhysteron sp. AS21B
title Spirobisnaphthalenes from the Mangrove-Derived Fungus Rhytidhysteron sp. AS21B
title_full Spirobisnaphthalenes from the Mangrove-Derived Fungus Rhytidhysteron sp. AS21B
title_fullStr Spirobisnaphthalenes from the Mangrove-Derived Fungus Rhytidhysteron sp. AS21B
title_full_unstemmed Spirobisnaphthalenes from the Mangrove-Derived Fungus Rhytidhysteron sp. AS21B
title_short Spirobisnaphthalenes from the Mangrove-Derived Fungus Rhytidhysteron sp. AS21B
title_sort spirobisnaphthalenes from the mangrove-derived fungus rhytidhysteron sp. as21b
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967209/
https://www.ncbi.nlm.nih.gov/pubmed/24663115
http://dx.doi.org/10.3390/md12031271
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AT chookpaiboonsupichar spirobisnaphthalenesfromthemangrovederivedfungusrhytidhysteronspas21b

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