Chemistry and Biology of Bengamides and Bengazoles, Bioactive Natural Products from Jaspis Sponges

Sponges corresponding to the Jaspidae family have proved to be a prolific source of bioactive natural products. Among these, the bengamides and the bengazoles stand out by virtue of their unprecedented molecular architectures and impressive biological profiles, including antitumor, antibiotic and an...

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Detalles Bibliográficos
Autores principales: García-Ruiz, Cristina, Sarabia, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967228/
https://www.ncbi.nlm.nih.gov/pubmed/24646945
http://dx.doi.org/10.3390/md12031580
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author García-Ruiz, Cristina
Sarabia, Francisco
author_facet García-Ruiz, Cristina
Sarabia, Francisco
author_sort García-Ruiz, Cristina
collection PubMed
description Sponges corresponding to the Jaspidae family have proved to be a prolific source of bioactive natural products. Among these, the bengamides and the bengazoles stand out by virtue of their unprecedented molecular architectures and impressive biological profiles, including antitumor, antibiotic and anthelmintic properties. As a consequence, intense research activity has been devoted to these compounds from both chemical and biological standpoints. This review describes in detail the research into these classes of natural products and the benefits they offer in chemistry and biology.
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spelling pubmed-39672282014-03-27 Chemistry and Biology of Bengamides and Bengazoles, Bioactive Natural Products from Jaspis Sponges García-Ruiz, Cristina Sarabia, Francisco Mar Drugs Review Sponges corresponding to the Jaspidae family have proved to be a prolific source of bioactive natural products. Among these, the bengamides and the bengazoles stand out by virtue of their unprecedented molecular architectures and impressive biological profiles, including antitumor, antibiotic and anthelmintic properties. As a consequence, intense research activity has been devoted to these compounds from both chemical and biological standpoints. This review describes in detail the research into these classes of natural products and the benefits they offer in chemistry and biology. MDPI 2014-03-18 /pmc/articles/PMC3967228/ /pubmed/24646945 http://dx.doi.org/10.3390/md12031580 Text en © 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
García-Ruiz, Cristina
Sarabia, Francisco
Chemistry and Biology of Bengamides and Bengazoles, Bioactive Natural Products from Jaspis Sponges
title Chemistry and Biology of Bengamides and Bengazoles, Bioactive Natural Products from Jaspis Sponges
title_full Chemistry and Biology of Bengamides and Bengazoles, Bioactive Natural Products from Jaspis Sponges
title_fullStr Chemistry and Biology of Bengamides and Bengazoles, Bioactive Natural Products from Jaspis Sponges
title_full_unstemmed Chemistry and Biology of Bengamides and Bengazoles, Bioactive Natural Products from Jaspis Sponges
title_short Chemistry and Biology of Bengamides and Bengazoles, Bioactive Natural Products from Jaspis Sponges
title_sort chemistry and biology of bengamides and bengazoles, bioactive natural products from jaspis sponges
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967228/
https://www.ncbi.nlm.nih.gov/pubmed/24646945
http://dx.doi.org/10.3390/md12031580
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