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Chronic Kidney Disease Stage Is a Modulator on the Association between High-Sensitivity C-Reactive Protein and Coronary Vasospastic Angina

The prevalence of coronary vasospasm and also the factors associated with coronary vasospasm in CKD is still unclear. In this cross-sectional study of 859 consecutive CKD patients with angina pectoris received coronary catheterization, we evaluated the factors associated with coronary vasospasm. Pat...

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Autores principales: Hsu, Heng-Jung, Yen, Chiung-Hui, Hsu, Kuang-Hung, Wu, I-Wen, Lee, Chin-Chan, Sun, Chiao-Yin, Chou, Chia-Chi, Chen, Chun-Yu, Yang, Shih-Ying, Tsai, Chi-Jen, Wu, Mai-Szu, Hung, Ming-Jui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967392/
https://www.ncbi.nlm.nih.gov/pubmed/24737995
http://dx.doi.org/10.1155/2014/852507
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author Hsu, Heng-Jung
Yen, Chiung-Hui
Hsu, Kuang-Hung
Wu, I-Wen
Lee, Chin-Chan
Sun, Chiao-Yin
Chou, Chia-Chi
Chen, Chun-Yu
Yang, Shih-Ying
Tsai, Chi-Jen
Wu, Mai-Szu
Hung, Ming-Jui
author_facet Hsu, Heng-Jung
Yen, Chiung-Hui
Hsu, Kuang-Hung
Wu, I-Wen
Lee, Chin-Chan
Sun, Chiao-Yin
Chou, Chia-Chi
Chen, Chun-Yu
Yang, Shih-Ying
Tsai, Chi-Jen
Wu, Mai-Szu
Hung, Ming-Jui
author_sort Hsu, Heng-Jung
collection PubMed
description The prevalence of coronary vasospasm and also the factors associated with coronary vasospasm in CKD is still unclear. In this cross-sectional study of 859 consecutive CKD patients with angina pectoris received coronary catheterization, we evaluated the factors associated with coronary vasospasm. Patients with vasospasm were older and had higher peripheral blood white cell counts, higher peripheral blood monocyte cell counts, higher haemoglobin levels, higher hs-CRP levels, and lower levels of serum creatinine than patients without vasospasm. The results of multivariate logistic regression analysis revealed that peripheral blood monocyte count and hs-CRP level were independently associated with coronary vasospasm in patients with stage 1 CKD. Only peripheral blood monocyte count but not hs-CRP was independently associated with coronary vasospasm in patients with stages 2 and 3 of CKD. In conclusion, peripheral blood monocyte count is independently associated with coronary vasospasm in patients with stage 1–3 CKD, whereas hs-CRP is only independently associated with coronary vasospasm in patients with stage 1 CKD.
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spelling pubmed-39673922014-04-15 Chronic Kidney Disease Stage Is a Modulator on the Association between High-Sensitivity C-Reactive Protein and Coronary Vasospastic Angina Hsu, Heng-Jung Yen, Chiung-Hui Hsu, Kuang-Hung Wu, I-Wen Lee, Chin-Chan Sun, Chiao-Yin Chou, Chia-Chi Chen, Chun-Yu Yang, Shih-Ying Tsai, Chi-Jen Wu, Mai-Szu Hung, Ming-Jui ScientificWorldJournal Clinical Study The prevalence of coronary vasospasm and also the factors associated with coronary vasospasm in CKD is still unclear. In this cross-sectional study of 859 consecutive CKD patients with angina pectoris received coronary catheterization, we evaluated the factors associated with coronary vasospasm. Patients with vasospasm were older and had higher peripheral blood white cell counts, higher peripheral blood monocyte cell counts, higher haemoglobin levels, higher hs-CRP levels, and lower levels of serum creatinine than patients without vasospasm. The results of multivariate logistic regression analysis revealed that peripheral blood monocyte count and hs-CRP level were independently associated with coronary vasospasm in patients with stage 1 CKD. Only peripheral blood monocyte count but not hs-CRP was independently associated with coronary vasospasm in patients with stages 2 and 3 of CKD. In conclusion, peripheral blood monocyte count is independently associated with coronary vasospasm in patients with stage 1–3 CKD, whereas hs-CRP is only independently associated with coronary vasospasm in patients with stage 1 CKD. Hindawi Publishing Corporation 2014-03-05 /pmc/articles/PMC3967392/ /pubmed/24737995 http://dx.doi.org/10.1155/2014/852507 Text en Copyright © 2014 Heng-Jung Hsu et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Hsu, Heng-Jung
Yen, Chiung-Hui
Hsu, Kuang-Hung
Wu, I-Wen
Lee, Chin-Chan
Sun, Chiao-Yin
Chou, Chia-Chi
Chen, Chun-Yu
Yang, Shih-Ying
Tsai, Chi-Jen
Wu, Mai-Szu
Hung, Ming-Jui
Chronic Kidney Disease Stage Is a Modulator on the Association between High-Sensitivity C-Reactive Protein and Coronary Vasospastic Angina
title Chronic Kidney Disease Stage Is a Modulator on the Association between High-Sensitivity C-Reactive Protein and Coronary Vasospastic Angina
title_full Chronic Kidney Disease Stage Is a Modulator on the Association between High-Sensitivity C-Reactive Protein and Coronary Vasospastic Angina
title_fullStr Chronic Kidney Disease Stage Is a Modulator on the Association between High-Sensitivity C-Reactive Protein and Coronary Vasospastic Angina
title_full_unstemmed Chronic Kidney Disease Stage Is a Modulator on the Association between High-Sensitivity C-Reactive Protein and Coronary Vasospastic Angina
title_short Chronic Kidney Disease Stage Is a Modulator on the Association between High-Sensitivity C-Reactive Protein and Coronary Vasospastic Angina
title_sort chronic kidney disease stage is a modulator on the association between high-sensitivity c-reactive protein and coronary vasospastic angina
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967392/
https://www.ncbi.nlm.nih.gov/pubmed/24737995
http://dx.doi.org/10.1155/2014/852507
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