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Increased Survival in B-Cell-Deficient Mice during Experimental Cerebral Malaria Suggests a Role for Circulating Immune Complexes

The pathogenesis of malaria, an insect-borne disease that takes millions of lives every year, is still not fully understood. Complement receptor 1 (CR1) has been described as a receptor for Plasmodium falciparum, which causes cerebral malaria in humans. We investigated the role of CR1 in an experime...

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Detalles Bibliográficos
Autores principales: de Oliveira, Rosane B., Wang, Jennifer P., Ram, Sanjay, Gazzinelli, Ricardo T., Finberg, Robert W., Golenbock, Douglas T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967524/
https://www.ncbi.nlm.nih.gov/pubmed/24643866
http://dx.doi.org/10.1128/mBio.00949-14