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Viral Quasispecies Assembly via Maximal Clique Enumeration

Virus populations can display high genetic diversity within individual hosts. The intra-host collection of viral haplotypes, called viral quasispecies, is an important determinant of virulence, pathogenesis, and treatment outcome. We present HaploClique, a computational approach to reconstruct the s...

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Detalles Bibliográficos
Autores principales:	Töpfer, Armin, Marschall, Tobias, Bull, Rowena A., Luciani, Fabio, Schönhuth, Alexander, Beerenwinkel, Niko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967922/ https://www.ncbi.nlm.nih.gov/pubmed/24675810 http://dx.doi.org/10.1371/journal.pcbi.1003515

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