An Insulin-to-Insulin Regulatory Network Orchestrates Phenotypic Specificity in Development and Physiology

Insulin-like peptides (ILPs) play highly conserved roles in development and physiology. Most animal genomes encode multiple ILPs. Here we identify mechanisms for how the forty Caenorhabditis elegans ILPs coordinate diverse processes, including development, reproduction, longevity and several specifi...

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Detalles Bibliográficos
Autores principales: Fernandes de Abreu, Diana Andrea, Caballero, Antonio, Fardel, Pascal, Stroustrup, Nicholas, Chen, Zhunan, Lee, KyungHwa, Keyes, William D., Nash, Zachary M., López-Moyado, Isaac F., Vaggi, Federico, Cornils, Astrid, Regenass, Martin, Neagu, Anca, Ostojic, Ivan, Liu, Chang, Cho, Yongmin, Sifoglu, Deniz, Shen, Yu, Fontana, Walter, Lu, Hang, Csikasz-Nagy, Attila, Murphy, Coleen T., Antebi, Adam, Blanc, Eric, Apfeld, Javier, Zhang, Yun, Alcedo, Joy, Ch'ng, QueeLim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967928/
https://www.ncbi.nlm.nih.gov/pubmed/24675767
http://dx.doi.org/10.1371/journal.pgen.1004225

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