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Identification of New IκBα Complexes by an Iterative Experimental and Mathematical Modeling Approach
The transcription factor nuclear factor kappa-B (NFκB) is a key regulator of pro-inflammatory and pro-proliferative processes. Accordingly, uncontrolled NFκB activity may contribute to the development of severe diseases when the regulatory system is impaired. Since NFκB can be triggered by a huge va...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967930/ https://www.ncbi.nlm.nih.gov/pubmed/24675998 http://dx.doi.org/10.1371/journal.pcbi.1003528 |