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The checkpoint-dependent nuclear accumulation of Rho1p exchange factor Rgf1p is important for tolerance to chronic replication stress

Guanine nucleotide exchange factors control many aspects of cell morphogenesis by turning on Rho-GTPases. The fission yeast exchange factor Rgf1p (Rho gef1) specifically regulates Rho1p during polarized growth and localizes to cortical sites. Here we report that Rgf1p is relocalized to the cell nucl...

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Detalles Bibliográficos
Autores principales:	Muñoz, Sofía, Manjón, Elvira, García, Patricia, Sunnerhagen, Per, Sánchez, Yolanda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967976/ https://www.ncbi.nlm.nih.gov/pubmed/24478458 http://dx.doi.org/10.1091/mbc.E13-11-0689

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